SCREENING OF ACTIVE COMPOUNDS FROM Artemisia annua USING HFC-134A SUBCRITIC EXTRACTION SYSTEM

Journal of Tropical Pharmacy and Chemistry

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Title SCREENING OF ACTIVE COMPOUNDS FROM Artemisia annua USING HFC-134A SUBCRITIC EXTRACTION SYSTEM
 
Creator Lelono, Arthur
Simanungkalit, Sabar
Umarudin, Ibnu
Herdiawan, Herlan
 
Description Artemisia annua is known as the source of artemisinin, a sesqueterpene lactone possessing endoperoxide moeity with antiplasmodium activity. Sub-critical extraction of artemisinin from Artemisia annua using R134a solvent was conducted. A close system cycle process was constructed to investigate the ability of R134a to extract artemisinin together with other active compounds. Artemisinin and other isolated compouds yield was investigated at 30°C and presure process at 10 barr, with variation of process time. The extracted product was analysed as artemisinin as the target compounds with several isolated compounds as by product. Artemisinin content was reported ranging up to 0,5%, and the sub critic system was reported to be more efficient and effective comparing to other conventional extraction methods. The phytonics HFC-134a sub critics process can be used for extraction in selected pharmacologically active products from herbal plants.
 
Publisher Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117
 
Date 2018-07-26
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/149
10.25026/jtpc.v4i3.149
 
Source Journal of Tropical Pharmacy and Chemistry; Vol 4 No 3 (2018): Journal of Tropical Pharmacy and Chemistry; 114-121
2407-6090
2087-7099
10.25026/jtpc.v4i3
 
Language eng
 
Relation https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/149/152
 
Rights Copyright (c) 2018 Journal of Tropical Pharmacy and Chemistry
http://creativecommons.org/licenses/by-nc/4.0
 

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