Synthesis of Alginate/Nanocellulose bionanocomposite for in vitro delivery of Ampicillin

International Journal of Drug Delivery

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Field Value
 
Title Synthesis of Alginate/Nanocellulose bionanocomposite for in vitro delivery of Ampicillin
 
Creator Poonguzhali, R; Department of Chemistry, Auxilium College, Vellore 632 006, India
Basha, S Khaleel; Department of Chemistry, C. Abdul Hakeem College, Melvisharam 632 509, India
kumari, V sugantha; Department of Chemistry, Auxilium College, Vellore 632 006, India
 
Subject Drug Delivery
Alginate ; Nanocellulose ; Ampicillin ; Drug release ; Swelling property
 
Description In this study Ampicillin drug loaded with alginate and nanocellulose film was prepared by solution casting method. Nanocellulose and ampicillin incorporated into alginate to improve both mechanical and swelling property. The formulated ampicillin loaded Alg/NC film gave acceptable physicochemical properties compared with Alg-amp film and was able to deliver the drug in a prolonged release pattern. In vitro drug release showed that alginate, could provide an immediate release of ampicillin with further enhanced nanocellulose, and followed by a sustained release over 500 min of the remaining drug. The present study exhibited a simple and useful approach to systematically design for providing drug release profiles.
 
Publisher Advanced Research Journals
 
Contributor -
 
Date 2018-01-23
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://www.arjournals.org/index.php/ijdd/article/view/2168
10.5138/09750215.2168
 
Source International Journal of Drug Delivery; Vol 9, No 4 (2017): International Journal of Drug Delivery; 107-111
0975-0215
 
Language eng
 
Relation http://www.arjournals.org/index.php/ijdd/article/view/2168/pdf
 
Rights Copyright (c) 2017 R. Poonguzhali; S. Khaleel Basha; V. Sugantha Kumari
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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