COMPARISON OF EFFICACY OF INFUSIONS OF DEXMEDETOMIDINE VERSUS BUTORPHANOL AS SEDATIVE & ANALGESIC IN SHORT GENERAL ANAESTHESIA IN DAY CARE GYNAECOLOGICAL SURGERIES

IJAR - Indian Journal of Applied Research

View Publication Info
 
 
Field Value
 
Title COMPARISON OF EFFICACY OF INFUSIONS OF DEXMEDETOMIDINE VERSUS BUTORPHANOL AS SEDATIVE & ANALGESIC IN SHORT GENERAL ANAESTHESIA IN DAY CARE GYNAECOLOGICAL SURGERIES
 
Creator Agrawal, Dr. Anuja; Assisstant Professor, Department of Anaesthesia, Dhiraj Hospital, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara-391760 - Corresponding Author
Chauhan, Dr. Jitender; Third Year Anaesthesia Resident, Department of Anaesthesia, Dhiraj Hospital, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara-391760
Parikh, Dr. Hetal; Ex- Prof & HOD, Department of Anaesthesia, Dhiraj Hospital, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara-391760
 
Subject
 
Description Background And Goals: Development of selective alpha 2 adrenoceptor agonists may provide a new concept for the administration of periopertive anaesthesia & analgesia in day care surgeries. Goal of this study was to compare Inj.Dexmedetomidine & Inj.Butorphanol with respect to time required for onset & offset of sedation, quality of intraoperative as well as postoperative analgesia & the time required for post-operative recovery. Methods: After obtaining permission from Institutional Ethical Committee (IEC), study was conducted in 40 patients of ASA I and II divided into 2 groups A & B by computer generated random number table. Patients, in group A received inj  Dexmedetomidine 1 mcg/kg i.v and group B received inj. Butorphanol 10 mcg/kg i.v, in infusion over 10 minutes prior to induction. Induction was done with inj Propofol i.v 2mg/kg & maintained with 33% O2, 66%N2O & 0.6-0.8% of isoflurane with patient breathing spontaneously. Throughout the surgery the sedation and analgesia was maintained with inj Dexmedetomidine 0.7 microgram/kg/hr infusion in group A and with inj Butorphanol 2 microgram/kg/hr in group B. Patients were evaluated in postoperative recovery room with help of Visual Analogue Scale (VAS) for pain, Ramsay Sedation Score & Standard Aldrete Score for recovery. Results: Demographically, the two groups were similar. Requirement of inhalational anaesthetic agents was significantly reduced in the group A (p < 0.05).VAS was significantly less(2.75 ± 0.44) in the group B after 90 min and earlier rescue analgesia was given in group A ( p < 0.05). Eye opening was earlier (45.5 ± 23.61) in group A and was highly significant (p < 0.001). Postop recovery was significantly improved (9.8 ± 0.41) with dexmeditomidine group. Conclusion: Dexmedetomidine produces better sedation and analgesia without significant adverse effects and can be used as sole sedative and analgesic for day care surgery patients with better recovery.
 
Publisher World Wide Journals
 
Contributor
 
Date 2017-10-28
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://worldwidejournals.in/ojs/index.php/ijar/article/view/17
 
Source IJAR - Indian Journal of Applied Research; Vol 7, No 9 (2017): September
2249 - 555X
 
Language eng
 
Relation http://worldwidejournals.in/ojs/index.php/ijar/article/view/17/17
http://worldwidejournals.in/ojs/index.php/ijar/article/downloadSuppFile/17/18
 
Rights Copyright (c) 2017 Dr. Anuja Agrawal, Dr. Jitender Chauhan, Dr. Hetal Parikh
http://creativecommons.org/licenses/by/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library