A Facile One-pot Synthesis of New Pyrazolopyrimidines and Pyrazolo Pyridines Derivatives


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Field Value
Title A Facile One-pot Synthesis of New Pyrazolopyrimidines and Pyrazolo Pyridines Derivatives
Creator Ahmed, Hatem Abdel Moniem
Subject Organic Chemistry
substituted-5-amino-4-cyanopyrazoles; pyrazolo [3, 4-d] pyrimidines; pyrazolo [3, 4-b] pyridines; diethylmalonate; malononitrile and antibacterial activity
Description A Simple Facile One-pot reaction, novel and efficient rout for the synthesis of substituted pyrazolo [3, 4-d] pyrimidines, and pyrazolo [3, 4-b] pyridines, results from reaction of substituted-5-amino-4-cyanopyrazoles with malononitrile and diethylmalonate respectively. The structures of the products and conceivable mechanisms are discussed. The antibacterial activity of some new synthesized compounds was evaluated and seemed to be significant.
Publisher CIRWORLD
Date 2016-12-20
Type info:eu-repo/semantics/article
Peer-reviewed Article
Format application/pdf
Identifier http://cirworld.com/index.php/jac/article/view/4034
Source JOURNAL OF ADVANCES IN CHEMISTRY; Vol 8 No 1; 1533-1538
Language eng
Relation http://cirworld.com/index.php/jac/article/view/4034/3934
Rights Copyright (c) 2014 Journal of Advances in Chemistry

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