A Facile One-pot Synthesis of New Pyrazolopyrimidines and Pyrazolo Pyridines Derivatives

JOURNAL OF ADVANCES IN CHEMISTRY

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Field Value
 
Title A Facile One-pot Synthesis of New Pyrazolopyrimidines and Pyrazolo Pyridines Derivatives
 
Creator Ahmed, Hatem Abdel Moniem
 
Subject Organic Chemistry
substituted-5-amino-4-cyanopyrazoles; pyrazolo [3, 4-d] pyrimidines; pyrazolo [3, 4-b] pyridines; diethylmalonate; malononitrile and antibacterial activity
 
Description A Simple Facile One-pot reaction, novel and efficient rout for the synthesis of substituted pyrazolo [3, 4-d] pyrimidines, and pyrazolo [3, 4-b] pyridines, results from reaction of substituted-5-amino-4-cyanopyrazoles with malononitrile and diethylmalonate respectively. The structures of the products and conceivable mechanisms are discussed. The antibacterial activity of some new synthesized compounds was evaluated and seemed to be significant.
 
Publisher CIRWORLD
 
Date 2016-12-20
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://cirworld.com/index.php/jac/article/view/4034
 
Source JOURNAL OF ADVANCES IN CHEMISTRY; Vol 8 No 1; 1533-1538
2321-807X
 
Language eng
 
Relation http://cirworld.com/index.php/jac/article/view/4034/3934
 
Rights Copyright (c) 2014 Journal of Advances in Chemistry
http://creativecommons.org/licenses/by/4.0
 

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