Assessment of the Level of Interleukin IL 5 and IL 17 in Patients Infected with some Intestinal Parasites and H. pylori

International Journal for Research in Applied Sciences and Biotechnology

View Publication Info
 
 
Field Value
 
Title Assessment of the Level of Interleukin IL 5 and IL 17 in Patients Infected with some Intestinal Parasites and H. pylori
 
Creator Firas Fahad Habeeb
Ali Mohammed Abed
 
Subject H. pylori
IL 5
IL 17
protozoa
ELISA
fecal sample
serum
 
Description The current study aimed to assess the level of interleukin IL 5 and IL 17 in patients infected with E. histolytica, G. lamblia parasites and H. pylori who suffer from diarrhea and some intestinal disorders, who attended Shirqat General Hospital / Salah al-Din Governorate, during the period from October 2020 to March 2021. The number of faecal samples examined was 409. The parasite infection were detected and investigated using direct wet smear and ether-formalin precipitation methods using light microscopy. All positive samples were examined for microscopic examination by antigen test for faecal samples and antibody test for rapid serum samples for detection of H. pylori co-infection of intestinal protozoa. The results showed that the total infection rate was 46 (11.24%) positive sample for the intestinal protozoa and 363 (88.7%) negative sample, E. histolytica was the higher with 67.38%, followed by Giardia lamblia with 32.61%. The results of the bacterial detection showed that 13 (28.26) positive samples and 33 (71.73%) negative samples, and the rate of co-infection between E. histolytica and H. pylori 9 (29.03%) was higher than the infection rate between Giardia lamblia and H. pylori 4 (26.66%). As for evaluating the level of Cytokines studied, the concentrations of some anti-inflammatory kinetics such as interleukin-5 and some pro-inflammatory kinetics such as interleukin-17 were estimated using ELISA technique. The results showed an increase in the concentration of interleukin-5 in the serum of patients with intestinal protozoa infections, as its concentration reached (10.956 ± 2.381 ml/Pg) compared to the control group (4.334 ± 1.434 ml/Pg), As for the patients infected with H. pylori (4.284±1.260 ml/Pg), there was no increase in the concentration of interleukin-5 compared to the control group (the healthy ones), While the concentration of IL-17 was lower in patients with intestinal protozoa infections (30.114 ± 4.877 ml/Pg) compared to the control group (35.665 ± 3.198 ml/Pg), As well as in patients infected with H. pylori bacteria (31.097±2.001 pg/ml) compared to the control group. The results of the statistical analysis showed that there were significant significant differences in the concentration of each of interleukin 5 and 17, which were statistically significant at the level of probability ≤ 0.01 P.
 
Publisher Vandana Publications
 
Date 2021-11-06
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://www.ijrasb.com/ojs/index.php/ojs-ijrasb/article/view/440
10.31033/ijrasb.8.6.2
 
Source International Journal for Research in Applied Sciences and Biotechnology; Vol. 8 No. 6 (2021): November Issue; 4-9
2349-8889
 
Language eng
 
Relation https://www.ijrasb.com/ojs/index.php/ojs-ijrasb/article/view/440/330
 
Rights Copyright (c) 2021 International Journal for Research in Applied Sciences and Biotechnology
https://creativecommons.org/licenses/by-nc-nd/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library