Myringoplasty with Morphological Rationale of Application of Xenoperitoneum Decellularized Matrix in Experiment

Open Access Macedonian Journal of Medical Sciences

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Title Myringoplasty with Morphological Rationale of Application of Xenoperitoneum Decellularized Matrix in Experiment
Creator Yesniyazov, Dias
Maida, Tussupbekova
Abatov, Nurkasi
Yukhnevich, Yekaterina
Badyrov, Ruslan
Subject Decellularized matrix
Biological implant
Tympanic membrane perforation
Description AIM: The aim of the study is to create a myringoplasty technique with decellularized matrix of xenoperitoneum in an experiment on rabbits with morphological rationale of a new biological material application.
Sixty rabbits were included in research. The animals were randomly divided in two groups for use the bioimplant – decellularized matrix of xenoperitoneum and control. Each subgroup corresponded to the observation period and the removal of the animal from the experiment. Observation period was: 7 days, 21 days and 30 days after myringoplasty.
The maturation of connective tissue in both groups was completed by the 30th day. But the change in the exudative phase into the proliferative phase occurred faster and the dynamics of reparative processes after myringoplasty were better in experimental group.
The use the decellularized matrix of xenoperitoneum had better reparative properties
Publisher Scientific Foundation SPIROSKI, Skopje, Republic of Macedonia
Date 2021-10-05
Type info:eu-repo/semantics/article
Format application/pdf
Source Open Access Macedonian Journal of Medical Sciences; Vol. 9 No. A (2021): A - Basic Sciences; 811-816
Language eng
Rights Copyright (c) 2021 Dias Yesniyazov, Tussupbekova Maida, Nurkasi Abatov, Yekaterina Yukhnevich, Ruslan Badyrov (Author)

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