Perbandingan Angiotensin II Receptor Blocker Candesartan vs Termisartan vs Valsartan pada Monitoring Tekanan Darah Pasien Chronic Kidney Disease

Jurnal Penelitian Kesehatan Suara Forikes

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Title Perbandingan Angiotensin II Receptor Blocker Candesartan vs Termisartan vs Valsartan pada Monitoring Tekanan Darah Pasien Chronic Kidney Disease
 
Creator FANDINATA, SELLY SEPTI; ACADEMY PHARMACY OF SURABAYA
Darmawan, Rizky; ACADEMY PHARMACY OF SURABAYA
 
Description Hypertension is a health problem that needs to be taken seriously because it is the most powerful killer disease in the world. Blood pressure is a determining factor to achieve and target BP. The recommended antihypertensive guidelines are ACEI, ARB, diuretic, CCB or B-blocker. ARBs have a cardiorenal protective effect. This study aims to compare the effectiveness of blood pressure drugs valsartan, termisartan and candesartan in hypertensive patients with chronic kidney disease. This study is a prospective observational cohort study by measuring blood pressure before and after at the 1st and 6th months and then processed using statistical analysis of the independent t-test and Wilcoxon. The results of this study obtained data as many as 72 patients who met the inclusion criteria consisting of 24 patients (candesartan), 27 patients (termisartan) and 21 patients (valsartan). The candesartan therapy group, the average difference in systolic decline was 18.46±16.14 mmHg and diastolic 2.04±15.16 mmHg with systolic pressure p value = 0.000, diastolic p value = 0.217. Termisartan therapy had an average difference in systolic pressure reduction of 18.19±12.12 mmHg and diastolic pressure of 9.44±8.01 mmHg with systolic p value = 0.000 and diastolic p value = 0.000. The valsartan therapy group averaged a difference in systolic decrease of 0.14±1.2 mmHg, diastolic 2.71±2.84 mmHg with systolic pressure p value = 0.766 and diastolic p value = 0.102. So that of the three antihypertensive drugs, the most effective ARB in lowering systolic and diastolic blood pressure is telmisartan

Keywords: blood pressure; termisartan; Chronic Kidney Disease
 
Publisher FORIKES
 
Contributor
 
Date 2022-01-31
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Identifier http://forikes-ejournal.com/index.php/SF/article/view/1520
10.33846/%x
 
Source Jurnal Penelitian Kesehatan "SUARA FORIKES" (Journal of Health Research "Forikes Voice"); Vol 13, No 1 (2022): Januari 2022
Jurnal Penelitian Kesehatan SUARA FORIKES; Vol 13, No 1 (2022): Januari 2022
2502-7778
2086-3098
10.33846/sf131
 
Language en
 
Relation http://forikes-ejournal.com/index.php/SF/article/downloadSuppFile/1520/405
 
Rights Copyright (c) 2021 SELLY SEPTI FANDINATA, Rizky Darmawan
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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