REVISÃO INTEGRATIVA SOBRE ATIVIDADE ANTITUMORAL DE MICROALGAS E CIANOBACTÉRIAS

Revista Valore - Revista Científica da FaSF Faculdade Sul Fluminense

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Title REVISÃO INTEGRATIVA SOBRE ATIVIDADE ANTITUMORAL DE MICROALGAS E CIANOBACTÉRIAS
 
Creator Bezerra, Raquel Pedrosa
de Arruda, Maria Carla Santana
Calaça, Priscilla Régia de Andrade
Cavalcanti, Vivianne Lays Ribeiro
Brandão, Romero Marcos Pedrosa Costa
Porto, Ana Lúcia Figueiredo
 
Description Resumo O câncer é considerado um problema de saúde pública e atualmente sua incidência tem aumentado em todo o mundo. Infelizmente, os métodos convencionais empregados no tratamento são causadores de efeitos colaterais incômodos, impulsionando a busca por novas terapias, principalmente de fontes naturais. As microalgas e cianobactérias tem demonstrado potencial no tratamento antitumoral, despertando interesse em pesquisas científicas. Esta revisão integrativa, utilizou artigos originais que analisaram a atividade antitumoral de bioativos extraídos de microalgas ou cianobactérias em modelos experimentais in vitro e/ou in vivo publicados em língua inglesa nas bases de dados PubMed (NCBI), Google scholar e os periódicos da CAPES entre 2009 e 2019. 107 artigos atenderam aos critérios de elegibilidade. Estes apresentaram 58 diferentes gêneros de microalgas e cianobactérias, sendo os gêneros Spirulina sp. e Chlorella sp. os mais relatados. O extrato aquoso e os compostos purificados ficocianina e β-caroteno são os mais promissores em diferentes linhagens, principalmente MCF-7 de tumor mamário. O principal mecanismo de ação destes compostos foi a inibição da proliferação de células tumorais. O número de artigos publicados sobre atividade antitumoral de bioativos obtidos destes microrganismos é crescente, no entanto a identificação dos compostos e o conhecimento sobre seus mecanismos de ação ainda são limitados.
 
Publisher FaSF
 
Contributor Fundação de amparo à ciencia e tecnologia do estado de Pernambuco- FACEPE
 
Date 2021-07-14
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://revistavalore.emnuvens.com.br/valore/article/view/554
10.22408/reva602021554e-6001
 
Source Revista Valore; v. 6 (2021): Revista Valore; e-6001
2526-043X
2525-9008
10.22408/reva602021
 
Language por
 
Relation https://revistavalore.emnuvens.com.br/valore/article/view/554/753
https://revistavalore.emnuvens.com.br/valore/article/downloadSuppFile/554/73
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