Invivo Effect Analysis of Rhodomyrtus tomentosa Leaf Ethanol Extract Against Escherichia coli

Medical Laboratory Technology Journal

View Publication Info
 
 
Field Value
 
Title Invivo Effect Analysis of Rhodomyrtus tomentosa Leaf Ethanol Extract Against Escherichia coli
 
Creator Noviani, Doris
Treasa, Adisty Dwi
Tasman Munaf, Ade Zakiya
Winarsih, Sri
Nur Hidayati, Dwi Yuni
Nooryanto, Mukhamad
Sutrisno, Sutrisno
 
Subject
Rhodomyrtus tomentosa; puerperium infections; Escherichia coli
 
Description Puerperium infection contributed 11 percent of 48.17 percent of maternal mortality during the puerperium period; one of the causes of increased risk of puerperium infection was bacteria Gram-negative Escherichia coli. Puerperium infection occurred because bacteria enter through the vagina, wounds on the insertion of the placenta, and other parts spread to blood throughout the body and damage the spleen, liver, and uterus. This research aimed to determine the effect of Rhodomyrtus tomentosa leaves ethanol extract (Rtl-EE) as an antibacterial on the spleen, liver, and uterus of Escherichia coli -induced puerperal infection model mice. Mice in the postnatal treatment group were induced by Escherichia coli bacteria intravaginally and given different doses of ethanol extract of Rhodomyrtus tomentosa leaves. Examination of bacterial colonies growth used pour plate method with EMBA media. The research results showed that the administration of Rtl-EE decreased the growth of bacterial colonies respectively in the liver 1280, 924, 330 CFU/mL; the uterus 1806, 1180, 874 CFU/mL; and the spleen 712, 112, 774 CFU/mL. Colony growth started to decrease at dose 1 of Rtl-EE (100mg/kg BW) of mice model of Escherichia coli -induced puerperal infection. Rhodomyrtus tomentosa leaves contain active compounds - phenols, flavonoids, saponins, tannins, alkaloids, and triterpenoids as antibacterial. Rtl-EE had an antibacterial effect by reducing the number of bacteria on the spleen, liver, and uterus of Escherichia coli -induced puerperal infection model mice. Further research needs to conduct to examine the toxic dose of Rhodomyrtus tomentosa leaves against Escherichia coli bacteria.
 
Publisher Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan
 
Contributor
 
Date 2021-07-18
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article

 
Format application/pdf
 
Identifier http://www.ejurnal-analiskesehatan.web.id/index.php/JAK/article/view/392
10.31964/mltj.v7i1.392
 
Source Medical Laboratory Technology Journal; Vol 7, No 1 (2021): June; 83-91
2461-0879
10.31964/mltj.v7i1
 
Language eng
 
Relation http://www.ejurnal-analiskesehatan.web.id/index.php/JAK/article/view/392/174
10.31964/mltj.v7i1.392.g174
 
Rights Copyright (c) 2021 Adisty Dwi Treasa
http://creativecommons.org/licenses/by-nc-sa/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library