Low Total Lymphocyte Count as the Risk of Hospital Acquired Malnutrition in Children

Molecular and Cellular Biomedical Sciences

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Field Value
 
Title Low Total Lymphocyte Count as the Risk of Hospital Acquired Malnutrition in Children
 
Creator Ekaputri, Dian Sulistya
Sidiartha, I Gusti Lanang
Pratiwi, I Gusti Ayu Putu Eka
 
Description Background: Hospital Acquired Malnutrition (HAM) is characterized by inadequate nutritional therapy and the risk of developing malnutrition during the hospital stay. In clinical practice, there are many measurements to determine nutritional status. Total lymphocyte count (TLC) is associated with impaired function of immune system in malnutrition. The purpose of this study was to evaluate the prognostic value of TLC to the occurrence of HAM in pediatric patients.Materials and Methods: This an observational study with a prospective cohort design. Subjects were assessed for weight at the first day of hospitalization, then the subjects were followed until they were discharged. Body weight was re-measured on discharge to determine the presence or absence of HAM. This research was conducted at Sanglah Hospital from May-December 2019. Subjects who met the inclusion and exclusion criteria were enrolled in the study.Results: Among 120 subjects, 55 subjects or 45.8% were malnourished on admission. Subjects with a low TLC compared to a normal TLC had a 3.9-fold risk of experiencing hospital acquired malnutrition (95% Confidence Interval: 1.59 to 7.19, p=0.001). Subjects who had a low TLC had HAM of 61.8%, while subjects who had a normal TLC had HAM of 32.3%. In multivariate analysis, low TLC was the only risk factor for HAM in this research.Conclusion: This study proved that low TLC is the risk of HAM. Total lymphocyte count could be used as predictor of the risk of HAM in hospitalization children.Keywords: hospital malnutrition, total lymphocyte, children
 
Publisher Cell and BioPharmaceutical Institute
 
Contributor none
 
Date 2021-07-06
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://cellbiopharm.com/ojs/index.php/MCBS/article/view/191
10.21705/mcbs.v5i2.191
 
Source Molecular and Cellular Biomedical Sciences; Vol 5, No 2 (2021); 68-73
2527-3442
2527-4384
 
Language eng
 
Relation https://cellbiopharm.com/ojs/index.php/MCBS/article/view/191/75
 
Rights Copyright (c) 2021 Dian Sulistya Ekaputri
 

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