Role of Rigid Medical Thoracoscopy in Diagnosing Exudative Pleural Effusions with Low Adenosine Deaminase

Academia Journal of Medicine

View Publication Info
 
 
Field Value
 
Title Role of Rigid Medical Thoracoscopy in Diagnosing Exudative Pleural Effusions with Low Adenosine Deaminase
 
Creator Malik, Javaid Ahmad
Mir, Elias
 
Subject Rigid thoracoscopy
medical thoracoscopy
pleuroscopy
pleural effusion
ADA
tuberculosis
lung malignancy
 
Description Background: Medical thoracoscopy (MT) performed in the evaluation of undiagnosed exudative pleural effusion (EPE) has a high diagnostic yield. In this study, we describe our experience of rigid MT in the evaluation of undiagnosed exudative pleural effusions (EPE) with low adenosine deaminase (ADA). Subjects and Methods:This is a retrospective analysis of RT pleural biopsies performed between July 2012 and June 2015 for diagnosing EPE. These patients had at least two pleural fluid samples negative for malignant cytology and ADA less than 65 IU/L. Here we report the yield and complications of pleural biopsies with RT. Results: Our yield of thoracoscopic pleural biopsies was 81% with malignancy as the commonest diagnosis in 46% patients. Malignant pleural effusion was caused commonly by adenocarcinoma (67%) followed by squamous cell carcinoma (17%), small cell lung cancer (8%) and lymphoma (8%). There was no case of mesothelioma. Biopsy revealed tuberculosis in 31%, vasculitis in 4%, nonspecific pleuritis (NSP) in 11% and normal pleural tissue in 8% subjects. The presence of nodules on CT scan and those on MT had no significant correlation (P > 0.1). ADA did not significantly differ between various biopsy confirmed diagnostic groups (P > 0.2). Minor complications that settled with conservative management developed in 3 patients (11.5%) and were significantly related to comorbidities (p < 0.05) but not to the biopsy result (P = 0.894). Conclusion: Since majority of the EPE turn out to be either malignancy of tuberculosis, a rigid MT evaluation should be considered in all such patients if the facility is available at the center. Rigid MT has high diagnostic yield and acceptable safety.
 
Publisher Dr Sanket Hiware, College of Medicine and Health Science, DireDawa University, Ethiopia.
 
Date 2021-06-17
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
application/xml
text/html
application/epub+zip
 
Identifier https://aijournals.com/index.php/ajm/article/view/1970
 
Source Academia Journal of Medicine; Vol 4 No 1 (2021): January-June 2021; 54-59
2663-8290
2663-8282
 
Language eng
 
Relation https://aijournals.com/index.php/ajm/article/view/1970/2352
https://aijournals.com/index.php/ajm/article/view/1970/2353
https://aijournals.com/index.php/ajm/article/view/1970/2354
https://aijournals.com/index.php/ajm/article/view/1970/2355
 
Rights Copyright (c) 2021 Author
https://creativecommons.org/licenses/by/4.0/
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library