Method development for determination of water content from various materials by spectrophotometry and it’s validation

International Journal of Drug Delivery

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Field Value
 
Title Method development for determination of water content from various materials by spectrophotometry and it’s validation
 
Creator Devhare, L D; Bajiraoji karanjekar college of pharmacy sakoli
Ghugare, A P; Department of Quality Assurance, Sharad Pawar College of Pharmacy, Wanadongri, Nagpur, Maharashtra, India.
Hatwar, B P; Bajiraoji Karanjekar College of Pharamacy,Sakoli,Bhandara, MH
Goupale, D; Bajiraoji Karanjekar College of Pharamacy,Sakoli,Bhandara, MH
 
Subject analytical chemistry
Water, pyridine, methanol and DMSO,UV-Spectrophotometric method
 
Description A simple, sensitive and accurate UV-Spectrophotometric method for the estimation of water in various organic solvent (pyridine, methanol and DMSO) and its validation by spectrophotometry has been developed and compared with Karlfischer method. standard solution of water in Pyridine , methanol and DMSO was scanned over the range of 800-400 nm in spectrum mode of spectrophotometer at medium scanning speed using U.V spectrophotometer 1600 lambda max of water was found was found to be 450nm, 420nm and 438 nm in pyridine, methanol and DMSO. Three standard solution of water obeyed the Beer-Lambert’s law and were found to be linear over the concentration range of 1-5 μg/ml. validation of method was done by spectroscopy., Percentage recoveries for pyridine, methanol and DMSO were found to be 99.58,99.71 and 99.92. 
 
Publisher Advanced Research Journals
 
Contributor
 
Date 2016-02-28
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://www.arjournals.org/index.php/ijdd/article/view/1791
 
Source International Journal of Drug Delivery; Vol 7, No 4 (2015): International Journal of Drug Delivery; 233-240
0975-0215
 
Language eng
 
Relation http://www.arjournals.org/index.php/ijdd/article/view/1791/pdf
 
Rights Copyright (c) 2015 Lalchand Dayanand Devhare
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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