A DESCRIPTIVE REVIEW ON VARIOUS LIPIDS AND TECHNIQUES USED IN FORMULATION OF SOLID LIPID NANOPARTICLES

International Journal of Drug Delivery

View Publication Info
 
 
Field Value
 
Title A DESCRIPTIVE REVIEW ON VARIOUS LIPIDS AND TECHNIQUES USED IN FORMULATION OF SOLID LIPID NANOPARTICLES
 
Creator Singh, Sukhwinder; Rayat-Bahra Institute of Pharmacy, Hoshiarpur (Punjb), India
Kumar, Rajesh; Rayat Bahra Institute of Pharmacy Hoshiarpur (Punjab)
Kamal, Sukhmeet Singh; Rayat-Bahra Institute of Pharmacy, Hoshiarpur (Punjb), India
Kaur, Daljit; Rayat-Bahra Institute of Pharmacy, Hoshiarpur (Punjb), India
Sharma, Amit; Rayat-Bahra Institute of Pharmacy, Hoshiarpur (Punjb), India
Katual, Manoj Kumar; Rayat Bahra Institute of Pharmacy Hoshiarpur (Punjab)
 
Subject
Lipid, Nanoparticles, Biodegradable, Sonication, Homogenization
 
Description Solid lipid nanopaticles (SLNs) emerged in early 1990s as a next-generation drug delivery system, an alternative to traditional colloidal carriers like liposomes, polymeric nanoparticles, emulsions etc. Their size range is between 1 to 1000 nm and their biodegradable and bioacceptable nature make them less toxic and thus better suited to patients. SLNs have got potential applications in pharmaceutical field, cosmetics, clinical medicine and other allied sciences. Presently, formulation scientists have been focusing on SLNs as colloidal drug carriers for incorporating hydrophilic as well as lipophilic drugs. The ability to incorporate drugs into nanocarriers offers a new prototype in drug delivery which can be used for drug targeting. They hold great promise for reaching the goal of controlled and site specific drug delivery. Furthermore, SLNs have got advantage of being introduced in the body by oral, parenteral and topical routes. So the present review attempts to enlighten various lipids used in SLNs, manufacturing techniques as well as the potential applications through various routes for a variety of disorders. Furthermore, the manuscript also focuses on the fate of these lipids (constituents of SLNs) in the body and their way out (i.e. elimination).
 
Publisher Advanced Research Journals
 
Contributor
 
Date 2016-12-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://www.arjournals.org/index.php/ijdd/article/view/1885
 
Source International Journal of Drug Delivery; Vol 8, No 3 (2016): International Journal of Drug Delivery; 66-76
0975-0215
 
Language eng
 
Relation http://www.arjournals.org/index.php/ijdd/article/view/1885/pdf
 
Rights Copyright (c) 2016 Sukhwinder Singh, Rajesh Kumar, Sukhmeet Singh Kamal, Daljit Kaur, Amit Sharma, Manoj Kumar Katual
http://creativecommons.org/licenses/by-nc-nd/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library