Formulation and evaluation of floating bioadhesive Doxofylline tablets

International Journal of Drug Delivery

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Field Value
 
Title Formulation and evaluation of floating bioadhesive Doxofylline tablets
 
Creator Nagaraju, Bhukya; K.V.K College Of Pharmacy, Department Of Pharmaceutics, JNTUH Hyderabad India.
Ramu, B; K.V.K College Of Pharmacy, Department Of Pharmaceutics, JNTUH Hyderabad India.
Saibaba, S V; K.V.K College Of Pharmacy, Department Of Pharmaceutics, JNTUH Hyderabad India.
Rajkamal, B; K.V.K College Of Pharmacy, Department Of Pharmaceutics, JNTUH Hyderabad India.
 
Subject phrmaceutics
Pharmaceutical Sciences; Pharmaceutics; Drug Delivery
 
Description In the present work, an attempt has been made to develop gastro retentive floating tablets of Doxofylline .HPMC K4M and carbopol were used as controlled release polymers. All the formulations were prepared by direct compression method on 12 station rotary tablet punching machine. The blend of all the formulations showed god flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. FH 5 was the best optimized floating formulation because it released drug completely in 12hrs.It was also observed that the increasing concentration of polymers had a retarding effect on the drug release from the polymer matrices.
 
Publisher Advanced Research Journals
 
Contributor
 
Date 2017-02-28
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://www.arjournals.org/index.php/ijdd/article/view/1871
10.5138/09750215.1871
 
Source International Journal of Drug Delivery; Vol 8, No 4 (2016): International Journal of Drug Delivery; 134-141
0975-0215
 
Language eng
 
Relation http://www.arjournals.org/index.php/ijdd/article/view/1871/pdf
 
Rights Copyright (c) 2016 B Ramu
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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