Description of Visfatin Adipokine and its Roles on Inflammation and Coronary Heart Disease: A Review Study

Medical Science Journal for Advance Research (MSJAR)

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Title Description of Visfatin Adipokine and its Roles on Inflammation and Coronary Heart Disease: A Review Study
 
Creator Al-Kraity, Assist. Prof. Dr. Wijdan Rajh Hamza
Faisal, Ali Hussein
Khaleel, Ali Nabeel
Naeaam, Mahmoud Tuama
Jabar, Ali Sattar
 
Subject Coronary heart diseases
Visfatin
adipokine
pre-B-cell colony-enhancing factor (PBEF)
 
Description Coronary heart disease (CHD) is a generic designation for a group of related syndromes resulting from myocardial ischemia – an imbalance between cardiac blood supply (perfusion) and myocardial oxygen demand. Visfatin (VF)  is a recently discovered adipokine with different functions, Visfatin is mainly found in visceral adipose tissue and mimics insulin in lowering plasma glucose levels and, Visfatin emerges as a player in the development and progression of atherosclerotic lesions by directly promoting smooth muscle cell proliferation, Aberrant angiogenesis is now considered a feature of the atherogenic process in both coronary and carotid diseases. This adipokine was previously known as a pre-B-cell colony-enhancing factor   (PBEF) or  Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) an enzyme that in humans is encoded by the NAMPT gene  and demonstrated to be an intracellular protein with a key enzyme role in nicotinamide adenine dinucleotide (NAD)
 
Publisher Research and Education Development (READ) Institute
 
Date 2021-03-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://medical.science.journal-asia.education/index.php/msjar/article/view/13
10.46966/msjar.v2i1.13
 
Source Medical Science Journal for Advance Research; Vol. 2 No. 1 (2021): March 2021 - Medical Science Journal for Advance Research; 10-14
2774-4892
2776-3870
10.46966/msjar.v2i1
 
Language eng
 
Relation https://medical.science.journal-asia.education/index.php/msjar/article/view/13/9
 
Rights Copyright (c) 2021 Assist. Prof. Dr. Wijdan Rajh Hamza Al-Kraity; Ali Hussein Faisal; Ali Nabeel Khaleel; Mahmoud Tuama Naeaam; Ali Sattar Jabar
https://creativecommons.org/licenses/by/4.0
 

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