The effect of non-surgical periodontal therapy on glycemic control and C1-reactive protein levels among type 2 diabetic patients with periodontitis: A clinical trial

Journal of Current Biomedical Reports

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Title The effect of non-surgical periodontal therapy on glycemic control and C1-reactive protein levels among type 2 diabetic patients with periodontitis: A clinical trial
 
Creator Moshtaghi Moghaddam, Mohammad
Keymoradzadeh, Arman
Ghorbandoust, Rashed
 
Subject Medicine; Dentistry; Biochemistery
Antibiotics; Diabetes; Non-surgical periodontal treatment; Periodontal Disease
 
Description It suggests that non-surgical periodontal therapy without systemic antibiotic therapy may not achieve a significant improvement in glycemic control and systemic inflammation in diabetic patients. However, it is important to highlight that the decision of whether or not to use antibiotics to treat periodontitis. Thus this study aimed to evaluate over 3 months the consequence of non-surgical periodontal treatment without systemic antibiotic therapy on serum levels of HbA1c and C-reactive protein (CRP). Forty-two participants with type 2 diabetes mellitus (DM) and moderate periodontal disease were randomized into intervention (IG) and control (CG) groups. The IG received non-surgical periodontal therapy in the form of full-mouth scaling and root planing. Participants were followed up for 3 months. The CG received non-surgical periodontal therapy after 3 months. Clinical parameters, including plaque index (PI), gingival bleeding index (GBI), probing pocket depth (PPD), clinical attachment level (CAL), and HbA1c and CRP levels, of all patients were recorded at baseline and after 3 months. A p-value less than 0.05 considered significant. At the end of 3 months, IG showed improvement in all the clinical parameters compared to CG. There were no significant differences in HbA1c and CRP after 3 months when compared to the baseline level in both groups. Clinical parameters were significantly improved by the employment of non-surgical periodontal treatment without systemic antibiotic therapy, but HbA1C and CRP levels were not significantly affected.
 
Publisher ParsPublisher
 
Contributor
 
Date 2021-03-06
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
application/pdf
 
Identifier https://jcbior.com/index.php/JCBioR/article/view/54
10.52547/JCBioR.2.1.32
 
Source Journal of Current Biomedical Reports; Vol 2, No 1 (2021). Jan-March; 32-37
2717-1906
 
Language eng
 
Relation https://jcbior.com/index.php/JCBioR/article/view/54/PDF
https://jcbior.com/index.php/JCBioR/article/view/54/Fa
https://jcbior.com/index.php/JCBioR/article/downloadSuppFile/54/38
https://jcbior.com/index.php/JCBioR/article/downloadSuppFile/54/39
 
Rights Copyright (c) 2021 © The Author(s)
https://creativecommons.org/licenses/by-nc/4.0
 

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