Antifungal Activity of Triterpenoids and Steroids Isolated from Pinus merkusii Bark Against Phanerochaete chrysosporium

Wood Research Journal

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Field Value
 
Title Antifungal Activity of Triterpenoids and Steroids Isolated from Pinus merkusii Bark Against Phanerochaete chrysosporium
 
Creator Masendra, Masendra
Purba, Brandon Arsito Verick
Lukmandaru, Ganis
 
Subject Pinus merkusii; bark; steroids; triterpenoids; antifungal; white-rot
 
Description The outer part of a tree, known as the bark, protects the internal tissues from external conditions and attacks from microorganisms. Its antifungal activities are due to the presence of chemicals in this bark. This study aimed at evaluating the toxicity of triterpenoids and steroids from the bark of Pinus merkusii against Phanerochaete chrysosporium (white-rot). The triterpenoids and steroids were isolated from n-hexane extract of the bark through column chromatography. Then, the antifungal activity was evaluated by measuring the growth rate of the fungus on potato dextrose agar (PDA) medium in a Petri dish. The isolation resulted in three triterpenoids (3β- methoxyserratt-14-en-21-one, serrate-14-en-3β,21β –diol, 3α,21β- dimethoxy-D14-serratene) and two steroids (β-sitosterol, Stigmast-4-en-3-one). There was more of antifungal activity with β-sitosterol and serrate-14-en-3β,21β –diol, due to presence of hydroxyl bond and their hydrophobicity.
 
Publisher Masyarakat Peneliti Kayu Indonesia
 
Contributor
 
Date 2021-01-26
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://www.ejournalmapeki.org/index.php/wrj/article/view/485
10.51850/wrj.2020.11.2.65-71
 
Source Wood Research Journal; Vol 11, No 2 (2020): Wood Research Journal; 65-71
2774-9320
2087-3840
 
Language eng
 
Relation http://www.ejournalmapeki.org/index.php/wrj/article/view/485/434
http://www.ejournalmapeki.org/index.php/wrj/article/downloadSuppFile/485/16
http://www.ejournalmapeki.org/index.php/wrj/article/downloadSuppFile/485/17
 
Rights Copyright (c) 2021 Wood Research Journal
 

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