The management of patient with osteoporosis in clinical practice


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Field Value
Title The management of patient with osteoporosis in clinical practice
Creator Degli Esposti, Luca
Giacomini, Elisa
Ghigi, Alessandro
Perrone, Valentina
Subject Adherence to therapies
Administrative databases
Therapeutic appropriateness
Description Osteoporosis is a systemic skeletal disorder characterized by increased bone fragility, which is associated with an enhanced fracture risk. The first fracture often represents indeed the clinical manifestation of this condition. In the present document we provided an overview of the economic and clinical impact of a not-adequate therapeutic appropriateness and suboptimal adherence to osteoporosis therapy, that are both widely reported in literature despite osteoporotic treatments have proved their efficacy in reducing fracture risk. Adequate treatment and adherence were reported to be associated with a lower risk of re-fracture and all-cause mortality. Moreover, healthcare costs in osteoporotic patients with previous fractures were significantly lower in those receiving osteoporosis treatment rather than among untreated patients. Nevertheless, these two key-factors are not improving over time. The measurement of indicators of adherence and therapeutic appropriateness allows to analyse the utilization profile of the drugs indicated for the treatment of osteoporosis and to evaluate the presence of possible deviation between the prescriptive behaviours observed in clinical practice and the recommendations reported in the guidelines. The periodic monitoring of such indicators together with prescribing audit activity could represent a useful tool for the optimization of osteoporosis management and to achieve a correct resource allocation. (Rheumatology)
Publisher AboutScience srl - Piazza Duca d'Aosta 12 - 20124 Milano MI (Italy)
Date 2021-01-15
Type info:eu-repo/semantics/article
Review article
Format application/pdf
Source AboutOpen; Vol. 8 No. 1 (2021): January-December 2021; 1-5
AboutOpen; V. 8 N. 1 (2021): January-December 2021; 1-5
Language eng
Rights Copyright (c) 2021 The authors

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