4-(3,4-Dichlorophenyl)-6-(Furan-2-yl)Pyrimidine-2-Thiol as Building Block in Heterocyclic Synthesis

JOURNAL OF ADVANCES IN CHEMISTRY

View Publication Info
 
 
Field Value
 
Title 4-(3,4-Dichlorophenyl)-6-(Furan-2-yl)Pyrimidine-2-Thiol as Building Block in Heterocyclic Synthesis
 
Creator EL-Hashash, M. A.
El-badry, Yaser Abdel-moemen
Morsy, J. M.
 
Subject Hydrazinylpyrimidine; Oxadiazolo-pyrimidine; Pyrazolo-pyrimidine; Thioxopyrimidine; Triazolo-pyrimidine.
 
Description Pyrimidine-2-thiol (1) has been synthesized via one-pot, three component synthesis. Its behavior towards nitrogen nucleophiles like hydrazine hydrate, ethylamine, piperidine, and 2-aminobenzoic acid has been studied. A speculation to explain the activities of the thioamide-iminothiol equilibrium based on their thermodynamic and kinetic control under the experimental conditions were investigated. The hydrazinopyrimidine 2 and aminocarbamoyl derivative 8 were used as key starting materials for synthesis of some interesting nitrogen bridgehead compounds 10-13, hydrazones 14-16, and some mixed and non-mixed heterocyclic systems 17-19 respectively.
 
Publisher CIRWORLD
 
Date 2009-09-17
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://cirworld.com/index.php/jac/article/view/2656
 
Source JOURNAL OF ADVANCES IN CHEMISTRY; Vol 5 No 2; 669-677
2321-807X
 
Language eng
 
Relation http://cirworld.com/index.php/jac/article/view/2656/2580
 
Rights Copyright (c) 2013 Journal of Advances in Chemistry
http://creativecommons.org/licenses/by/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library