EFEK PEMBERIAN SEDUHAN KAYU ULAR (Strychnos lucida) TERHADAP PENURUNAN ABNORMALITAS SPERMATOZOA MENCIT (Mus musculus) MODEL DIABETES MELITUS

RUMPHIUS Pattimura Biological Journal

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Title EFEK PEMBERIAN SEDUHAN KAYU ULAR (Strychnos lucida) TERHADAP PENURUNAN ABNORMALITAS SPERMATOZOA MENCIT (Mus musculus) MODEL DIABETES MELITUS
 
Creator Kunu, Marissa Beatrix
Baszary, Chomsa Dintasari Umi
Killay, Amos
 
Description Diabetes Mellitus (DM), known as diabetes or blood sugar disease, is a group of chronic diseases characterized by increased blood sugar level (hyperglycemia). Prolonged hyperglycemia conditions will cause an increase in ROS (Reactive Oxygen Spesies) production by the mitochondria, which then cause damage to the mitochondrial membrane resulting in loss of function of the mitochondrial membrane potential and can induce sperm cells apoptosis. This study aims to determine effect of kayu ular (Strychnos lucida) steeping on decreasing spermatozoa abnormalities of mice (Mus musculus) diabetes mellitus model. The result showed that administration of kayu ular steeping at concentration of 2,6gr/50ml was signicantly reduced (P<0.05) spermatozoa abnormality. This dose is the most effective concentration to decreased the spermatozoa abnormality of mice. This though to be due to the active compounds found in steeping kayu ular (Strychnos lucida) which can counteract free radicals due to diabetes mellitus that decreasing spermatozoa abnormalities.
 
Publisher Universitas Pattimura
 
Date 2020-10-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://ojs3.unpatti.ac.id/index.php/rumphius/article/view/2492
 
Source RUMPHIUS: Pattimura Biological Journal; Vol 2 No 2 (2020): RPBJ Vol 2 No 2 2020; 001-007
RUMPHIUS; Vol 2 No 2 (2020): RPBJ Vol 2 No 2 2020; 001-007
2684-804X
 
Language eng
 
Relation https://ojs3.unpatti.ac.id/index.php/rumphius/article/view/2492/2187
 
Rights Copyright (c) 2020 CHOMSA DINTASARI UMI BASZARY
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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