Adefovir dipivoxil nella terapia dell’epatite B cronica: profilo farmacologico clinico ed economico

Farmeconomia. Health economics and therapeutic pathways

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Field Value
 
Title Adefovir dipivoxil nella terapia dell’epatite B cronica: profilo farmacologico clinico ed economico
 
Creator Pradelli, Lorenzo
Eandi, Mario
 
Subject Pharmacoeconomics; Health economics
Chronic hepatitis B (CHB); Adefovir dipivoxil (ADV); Health care economics
 
Description Despite the fact that an effective vaccine against hepatitis B virus (HBV) has been available for over 30 years, the worldwide prevalence of this infection is still very high. Until recently, there were only two effective therapeutic options for chronic hepatitis B (CHB), interferon and lamivudine, but both are considered suboptimal therapies, for different reasons. Adefovir dipivoxil (ADV) is the oral prodrug of adefovir, an acyclic nucleotide analogue that demonstrated virological and clinical effectiveness against HBV in experimental and real world settings. In this paper the main pharmacological and clinical evidence of ADV in CHB is reviewed. Health care economics data on the direct costs of CHB in different countries are presented and potential economical consequences of its introduction in Italy are discussed.
 
Publisher SEEd Medical Publishers
 
Date 2005-12-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://journals.edizioniseed.it/index.php/FE/article/view/849
10.7175/fe.v6i4.849
 
Source Farmeconomia. Health economics and therapeutic pathways; Vol 6, No 4 (2005); 289-300
2240-256X
1721-6915
 
Language eng
 
Relation https://journals.edizioniseed.it/index.php/FE/article/view/849/933
 
Rights Copyright (c) 2005 Farmeconomia. Health economics and therapeutic pathways
http://creativecommons.org/licenses/by-nc/4.0
 

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