Formulation and Characterization of Zingiberol Loaded Microsphere for Motion Sickness

Cadernos de Campo: Revista de Ciências Sociais

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Title Formulation and Characterization of Zingiberol Loaded Microsphere for Motion Sickness
Creator Kar, Ayan Kumar
Shil, Arijit
Mahanty, Beduin
Description The present research work involve the development of Zingiberol as the treatment of motion sickness. The Zingiberol microsphere was formulated by Ionotropic gelation method using different polymers in different ratio depending on RSM method. The prepared formulations were optimized on the basis of dependent variables like particle size (mg), entrapment efficiency etc. The SEM photographs of Zingiberol microsphere before dissolution shows the spherical and smooth surface whereas after dissolution the pores and crevices were shown which is indicating that the microsphere are showing drug release by diffusion mechanism. The microsphere formulations were able to sustain the release of drug both in vitro and in vivo. In the stability studies no significant change in drug entrapment release characteristics of the microspheres.
Publisher Scholar Science Journals
Date 2019-11-30
Type info:eu-repo/semantics/article
Peer-reviewed Article
Format application/pdf
Source International Journal of Advances in Pharmaceutics; Vol 8 (2019): Continuous publication model; e5258
Language eng
Rights Copyright (c) 2019 International Journal of Advances in Pharmaceutics

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