Research Progress of Common Organic Guanidine Antibacterial Agents

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Field Value
 
Title Research Progress of Common Organic Guanidine Antibacterial Agents
 
Creator Hua Li
Yingping Qi
Yongfeng Shen
Hua Li
 
Subject Organic guanidine, alkyl guanidine, aryl guanidine, polymerized guanidine, physical and chemical properties, application, preparation method, germicidal mechanism; germicidal efficacy
 
Description Aim: The aim of this study is to investigate the antimicrobial properties of organic guanidine because of their strong alkalinity, high stability, low toxicity and good biological activity. Methods: By referring to the relevant domestic and foreign literature, the physical and chemical properties, uses, preparation methods, germicidal efficacy and germicidal mechanism of guanidine compounds commonly used in alkyl guanidine, aryl guanidine, and polymerized guanidine with antibacterial properties were briefly analyzed and summarized. Result: It has been found that dodecylguanidine acetate in long-chain alkyl monoguanidine, iminoctadine in long-chain alkyl biguanide, chlorhexidine in aryl guanidine, polyhexamethylene biguanide hydrochloride(PHMB)and polyhexamethylene guanidine hydrochloride(PHMG) in polymerized guanidine all had killing or inhibiting effects on bacteria, fungi and viruses. Conclusion: Guanidine compounds with broad-spectrum and high-efficiency bactericidal effect can not only be used as antibacterial agents alone, but also can be introduced into polymers to prepare materials with antibacterial properties, and the development prospect of organic guanidine antibacterial coatings is prospected.
 
Publisher PURKH
 
Date 2020-08-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://purkh.com/index.php/tochem/article/view/753
 
Source To Chemistry Journal; Vol. 6: May - August 2020; 163-174
2581-7507
 
Language eng
 
Relation https://purkh.com/index.php/tochem/article/view/753/783
 
Rights Copyright (c) 2020 Hua Li, Yingping Qi, Yongfeng Shen, Hua Li
https://creativecommons.org/licenses/by/4.0
 

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