Phytochemical investigation of seeds of Trachyspermum ammi Linn. by GC-MS

Journal of Chemistry, Environmental Sciences and its Applications

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Field Value
 
Title Phytochemical investigation of seeds of Trachyspermum ammi Linn. by GC-MS
 
Creator Ekta Sharma
B S Arora
 
Subject Phytochemical study
Trachyspermum ammi
GC-MS
ellagic acid
Thymol
Anticancer effect
Cytotoxicity
Sulforhodamine B assay
 
Description The present study embraces phytochemical investigation of the essential oil extracted from the mature seeds of Trachyspermum ammi Linn for different constituents by subjecting the oil to gas chromatography-mass spectrometry (GC-MS) analysis. The identification of the constituents is based upon retention indices and by comparison of their mass spectral fragmentation patterns against the commercial library mass spectra (Wiley, Nist etc.). Ellagic acid (EA), which is a natural phenol antioxidant, has been isolated from methanol extract from the mature seeds of Trachyspermum ammi Linn. Also, Thymol (Thl), a naturally occurring phenolic compound, has been crystallized by the reported standard procedure from oil extracted from these mature seeds. Both these compounds have been evaluated for their possible anti-cancer effect against a selected panel of human cancer cell lines by means of sulforhodamine B assay.
 
Publisher Chitkara University
 
Date 2017-03-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://jce.chitkara.edu.in/index.php/jce/article/view/21
10.15415/jce.2017.32007
 
Source Journal of Chemistry, Environmental Sciences and its Applications; Vol 3 No 2 (2017); 91-100
2349-7769
2349-7564
 
Language eng
 
Relation https://jce.chitkara.edu.in/index.php/jce/article/view/21/13
 
Rights Copyright (c) 2017 Ekta Sharma & B S Arora
https://creativecommons.org/licenses/by/4.0/
 

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