Origin, Stemness, Marker and Signaling Pathway of Oral Cancer Stem Cell

Molecular and Cellular Biomedical Sciences

View Publication Info
 
 
Field Value
 
Title Origin, Stemness, Marker and Signaling Pathway of Oral Cancer Stem Cell
 
Creator Rahmawati, Dicha Yuliadewi
Dwifulqi, Hernindya
Sandra, Ferry
 
Description Cancer constitutes of complex heterogeneous organ-like structures with a hierarchical cell structure, and only minor phenotypic subpopulations with stem-like properties have a dual capacity to indefinitely self-renew and generate all heterogeneous cell phenotypes consisting of bulk tumor cells. Cancer stem cells (CSC) has similar properties to ordinary stem cells. It is understood that CSC is responsible for the recurrence of metastasis and drug resistance. Thus, control of CSC can provide successful therapy intervention that inhibits cancer growth and aggressive behavior. Conventional cancer therapy is realized to be insufficient for oral cancer therapy. Meanwhile, accurate targeting of OCSC has proved to be a significant challenge due to the commonality of many markers between OCSC and healthy cells. This article discusses the current understanding of oral CSC, with focus on origin, stemness, marker and signalling pathway.Keywords: oral cancer stem cell, CSC, marker, origin, stemness, therapy
 
Publisher Cell and BioPharmaceutical Institute
 
Contributor
 
Date 2020-11-02
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://cellbiopharm.com/ojs/index.php/MCBS/article/view/159
10.21705/mcbs.v4i3.159
 
Source Molecular and Cellular Biomedical Sciences; Vol 4, No 3 (2020); 100-4
2527-3442
2527-4384
 
Language eng
 
Relation https://cellbiopharm.com/ojs/index.php/MCBS/article/view/159/59
 
Rights Copyright (c) 2020 Dicha Yuliadewi Rahmawati, Hernindya Dwifulqi, Ferry Sandra
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library