A Case of the Co-Existence of Subcorneal Pustular Dermatosis and Pyoderma Gangrenosum and a Review of the Literature

Open Access Macedonian Journal of Medical Sciences

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Field Value
 
Title A Case of the Co-Existence of Subcorneal Pustular Dermatosis and Pyoderma Gangrenosum and a Review of the Literature
 
Creator Ferrillo, Maria
Villani, Alessia
Fabbrocini, Gabriella
Mascolo, Massimo
Megna, Matteo
Costa, Claudia
Napolitano, Maddalena
 
Subject Subcorneal pustular dermatosis
Pyoderma gangrenosum
Sneddon-Wilkinson disease
neutrophilic dermatoses
Dermatology
 
Description BACKGROUND: Subcorneal pustular dermatosis, also known as Sneddon-Wilkinson disease, can be classified as one of the neutrophilic dermatoses together with pyoderma gangrenosum. The development of both SPD and PG in the same patient has rarely been reported and may be a strong indicator of IgA dysglobulinemiaCASE REPORT: We report the case of a 34-year-old woman with a 2-year history of relapsing pustular eruptions mainly affecting the abdomen, gluteus region, elbows, and the extremities. Four years after the onset of subcorneal pustular dermatosis (SPD), she developed pyoderma gangrenosum (PG) on her right hand. In literature, the coexistence of SPD and PG in the same patient has already been described. This co-occurrence might indicate a certain predisposition for immune dysregulation.CONCLUSION: Although the two NDs are often associated with systemic diseases, these patients should be followed up for any malignancy because of the strong association between these disorders.
 
Publisher Scientific Foundation SPIROSKI, Skopje, Republic of Macedonia
 
Date 2018-07-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Case report
 
Format application/pdf
application/pdf
 
Identifier https://www.id-press.eu/mjms/article/view/oamjms.2018.214
10.3889/oamjms.2018.214
 
Source Open Access Macedonian Journal of Medical Sciences; Vol. 6 No. 7 (2018): Jul 20 (OAMJMS); 1271-1274
1857-9655
 
Language eng
 
Relation https://www.id-press.eu/mjms/article/view/oamjms.2018.214/2269
https://www.id-press.eu/mjms/article/view/oamjms.2018.214/2234
 

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