Analytical method development and validation for the estimation of Mirabegron in pure and its solid dosage form by UV spectrophotometric method

International Journal of Research in Pharmaceutical Sciences and Technology

View Publication Info
 
 
Field Value
 
Title Analytical method development and validation for the estimation of Mirabegron in pure and its solid dosage form by UV spectrophotometric method
 
Creator Badike Kuruva Suresh
Nerusula Anusha
Anne Boyina Sravani
 
Subject Mirabegron
1N Hcl
UV Spectrophotometry
Betmiga
 
Description A simple, economical, rapid, accurate, precise spectrophotometric method has been developed and validated according to ICH Guidlines for the Mirabegron as active pharmaceutical ingredient (API) by UV spectrophotometric method. The absorption maxima of Mirabegron was found to be at 249 nm wavelength using 1N Hcl as a solvent. Linearity range was found to be 3-15μg/ml, with the correlation coefficient being more than 0.999. The relative standard deviation was found to be < 2%. The percentage recovery was within the range of 98% -105%, indicating that there is no significant interference from the other ingredients present in the formulation. The method can be applied for the routine analysis of Mirabegron as API in pharmaceutical preparation.
 
Publisher Rubatosis Publications
 
Date 2020-07-20
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://rubatosis.org/journals/index.php/ijrpst/article/view/207
10.33974/ijrpst.v1i4.207
 
Source International Journal of Research in Pharmaceutical Sciences and Technology; Vol 1 No 4 (2020): Volume 1 Issue 4; 146-150
2581-9143
 
Language eng
 
Relation https://rubatosis.org/journals/index.php/ijrpst/article/view/207/115
 
Rights Copyright (c) 2020 Badike Kuruva Suresh, N. Anusha, Anne Boyina Sravani
https://creativecommons.org/licenses/by-nc-sa/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library