Microbiome in Oral Squamous Cell Carcinoma: Mechanisms and Signaling Pathways

Molecular and Cellular Biomedical Sciences

View Publication Info
 
 
Field Value
 
Title Microbiome in Oral Squamous Cell Carcinoma: Mechanisms and Signaling Pathways
 
Creator Hayati, Nurani
Panjaitan, Caesary Cloudya
Sandra, Ferry
 
Description Oral squamous cell carcinoma is part of head and neck squamous cell carcinoma which is the ultimate cause of morbidity and mortality in cancer. The alteration of microbial community in the saliva might act as a helpful marker for the prediction, detection and prognosis oral cancer, particularly the transition of cancer precursor lesion. There are three mechanisms of action of oral microbiota in cancer pathogenesis, chronic inflammation of bacterial stimulation, carcinogenesis by cytoskeletal rearrangements, and carcinogenic substances that produced by microorganisms. Changes in the composition of microbiota could therefore have the potential to be used as a significant oral biomarker to predict the pathological transition from oral epithelial precursor lesion to cancer.Keywords: microbiome, oral cancer cellular proliferation, microorganism, oral cancer, oral squamous cell carcinoma
 
Publisher Cell and BioPharmaceutical Institute
 
Contributor
 
Date 2020-07-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://cellbiopharm.com/ojs/index.php/MCBS/article/view/160
10.21705/mcbs.v4i2.160
 
Source Molecular and Cellular Biomedical Sciences; Vol 4, No 2 (2020); 52-60
2527-3442
2527-4384
 
Language eng
 
Relation https://cellbiopharm.com/ojs/index.php/MCBS/article/view/160/58
 

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