The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus)

Journal of Parasite Science

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Field Value
 
Title The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus)
 
Creator Azkiana, Alfina
Setiawan, Boedi
Safitri, Erma
Suwanti, Lucia Tri
Mufasirin, Mufasirin
Legowo, Djoko
 
Subject
folic acid, Toxoplasma gondii, Mus musculus, foetus
 
Description This research aimed to investigate the effect of folic acid as supportive therapy of spiramycine on weight of foetus to Toxoplasma gondii-infected pregnant mice (Mus musculus). Twenty pregnant female mice were divided into four groups as C -, C +, T1 and T2. C +, T1 and T2 were infected by Toxoplasma gondii. C – and C + administered orally 0.5 ml aquadest, T1 administered orally 130 mg/kg BW spiramycine and 0.052 µg/g BW folic acid and T2 administered orally 0.052 µg/g BW folic acid. Experimental groups received the treatments for 5 days, then animals of each groups were sacrified. Foetuses were dissected out for observation. The weight of fetuses were measured using an analytical balance. The data weight of foetuses was presented descriptively and analyzed by ANOVA test and continued by Tukey HSD. From this study, the weight of foetuses from the pregnant mice of T1 and T2 have difference compared with the controls. The result of this research is folic acid affects the weight of foetuses to Toxoplasma gondii-infected pregnant mice.
 
Publisher Universitas Airlangga
 
Contributor
 
Date 2019-12-04
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://e-journal.unair.ac.id/JoPS/article/view/16432
10.20473/jops.v3i1.16432
 
Source Journal of Parasite Science; Vol 3, No 1 (2019): Journal of Parasite Science; 33-36
2656-5331
2599-0993
 
Language eng
 
Relation https://e-journal.unair.ac.id/JoPS/article/view/16432/8825
 
Rights Copyright (c) 2019 Journal of Parasite Science
http://creativecommons.org/licenses/by-nc-sa/4.0
 

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