Indole – the scent of a healthy “inner soil”

Microbial Ecology in Health and Disease

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Field Value
 
Title Indole – the scent of a healthy “inner soil”
 
Creator Berstad, Arnold
Raa, Jan
Valeur, Jørgen
 
Subject hydrogen peroxide; indole; indoleamine dioxygenase; irritable bowel syndrome; melatonin; tryptophan
 
Description Tryptophan is an essential amino acid with an indole nucleus. Humans cannot produce this amino acid themselves, but must obtain it through their diet. Much attention is currently paid to the wide physiological and clinical implications of the tryptophan-derived substances, serotonin and kynurenines, generated by human enzymes following the intestinal absorption of tryptophan. However, even before being absorbed, several microbial metabolites of tryptophan are formed, mainly from ‘malabsorbed’ (incompletely digested) proteins within the colon. The normal smell of human faeces is largely due to indole, one of the major metabolites. Recent studies indicate that this foul-smelling substance is also of utmost importance for our health.Keywords: hydrogen peroxide; indole; indoleamine dioxygenase; irritable bowel syndrome; melatonin; tryptophan(Published: 14 August 2015)Citation: Microbial Ecology in Health & Disease 2015, 26: 27997 - http://dx.doi.org/10.3402/mehd.v26.27997
 
Publisher Microbial Ecology in Health and Disease
 
Contributor
 
Date 2015-08-14
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
text/html
application/epub+zip
application/xml
 
Identifier http://www.microbecolhealthdis.net/index.php/mehd/article/view/27997
10.3402/mehd.v26.27997
 
Source Microbial Ecology in Health and Disease; Vol 26 (2015)
1651-2235
 
Language eng
 
Relation http://www.microbecolhealthdis.net/index.php/mehd/article/view/27997/41602
http://www.microbecolhealthdis.net/index.php/mehd/article/view/27997/41603
http://www.microbecolhealthdis.net/index.php/mehd/article/view/27997/41604
http://www.microbecolhealthdis.net/index.php/mehd/article/view/27997/41605
http://www.microbecolhealthdis.net/index.php/mehd/article/downloadSuppFile/27997/19897
 
Rights Copyright (c) 2015 Microbial Ecology in Health and Disease
http://creativecommons.org/licenses/by-nc/4.0
 

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