Triterpenoid compound from metanol extract of mangrove leaves (Sonneratia alba) and anti-cholesterol activity test

Jurnal Pendidikan Kimia

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Title Triterpenoid compound from metanol extract of mangrove leaves (Sonneratia alba) and anti-cholesterol activity test
 
Creator Musa, Weny J.A
Bialangi, Nurhayati
Situmeang, Boima
Silaban, Saronom
 
Subject
 
Description Mangrove plant (Sonneratia alba) is easily found in West and North Indonesia. Mangrove plant has the potential of being a herb medicine. Mangrove plant variously used in ethnomedicine to treat various deseases like wounds, diarrhea, and fever. In previously sutudy, leaf extract of mangrove plants reported have anti-cholesterol activity. This plant is widely used to treat various deseases like wounds, diarrhea, and fever. The purpose of this study was to isolate triterpenoid compound from the ethyl acetate fraction of mangrove leaves and anticholesterol activity test. Extraction was done by maceration method using methanol 96% as solvent. Isolation was carried out by column chromatography using a combination of n-hexane, ethyl acetate, and methanol solvents. The elucidation of the structure was determined by analysis of IR, 1H-NMR, 13C-NMR, 2D-NMR, and MS spectroscopies as well as by comparisons with the literature. Anticholesterol activity test was carried out in vitro. The results showed that triterpenoid compounds (lupeol) were able to reduce cholesterol from concentrations of 5, 10, 20, 40, 60, and 80 ppm are 13.7; 29.4; 49.0; 60,1; 70.2; and 77.0% respectively. Therefore, isolates compound (lupeol) have anti-cholesterol activity.Keywords:Anti-cholesterol; mangrove; triterpenes
 
Publisher Jurnal Pendidikan Kimia
 
Contributor
 
Date 2019-04-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://jurnal.unimed.ac.id/2012/index.php/jpk/article/view/13124
10.24114/jpkim.v11i1.13124
 
Source Jurnal Pendidikan Kimia; Vol 11, No 1 (2019): April 2019; 18-23
2549-3116
2085-3653
 
Language eng
 
Relation https://jurnal.unimed.ac.id/2012/index.php/jpk/article/view/13124/11117
 
Rights Copyright (c) 2019 JURNAL PENDIDIKAN KIMIA
 

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