Antiphospholipid Syndrome: A Review

Haematology Journal of Bangladesh

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Title Antiphospholipid Syndrome: A Review
Creator Hossain, Md. Motahar
Hossain, Md. Akhter
Rahman, Yasmin
Hasan, Md. Kamrul
Subject antiphospholipid syndrome
autoimmune disease
Description Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently positive levels of antiphospholipid antibodies. It may be primary or secondary. The latest classification criteria (Sydney 2006) recognize just three tests to define this syndrome- lupus anticoagulant, anticardiolipin antibodies and anti-?2-glycoprotein-1 antibodies. Treatment of thrombotic events involves lifelong anticoagulation with vitamin K antagonist warfarin. Antiphospholipid antibody syndrome (APS) with only pregnancy morbidity is treated with thromboprophylaxis with heparin during pregnancy and postpartum for 6 weeks. In this review we discuss the pathogenesis, diagnosis, treatment and prognosis of the APS.
Publisher Haematology Society of Bangladesh
Date 2020-05-13
Type info:eu-repo/semantics/article
Format text/html
Source Haematology Journal of Bangladesh; Vol. 2 No. 02 (2018); 51-58
Language eng
Rights Copyright (c) 2018 Md. Motahar Hossain, Md. Akhter Hossain, Yasmin Rahman, Md. Kamrul Hasan

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