Renal Function Evaluation in Secondary Amyloidosis According to Location of Deposition

Medical Laboratory Technology Journal

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Title Renal Function Evaluation in Secondary Amyloidosis According to Location of Deposition
Creator Özçelik, Serhat
Şahin, Gülizar Manga
Subject Internal Medicine; Nephrology
renal biopsy; deposition; secondary amyloidosis
Description It aimed to evaluate the renal functions according to the accumulation site of amyloid in patients diagnosed with secondary amyloidosis by renal biopsy. Fifty patients diagnosed with secondary amyloidosis, who referred to the nephrotic syndrome outpatient clinic included in the study. According to the findings of renal biopsy, only-glomerular amyloid deposition (group- 1) detected in 9 patients and glomerular+ tubulointerstitial deposition (group- 2) identified in 41 patients. Serum creatinine, creatinine clearance, and total proteinuria levels compared between groups at the time of presentation and on 3rd, 6th, 12th, and 24th months. Initial and subsequent serum creatinine, creatinine clearance, and total proteinuria levels not found to be significantly different between groups (p>0,05 for all). Among subjects with only-glomerular deposition, statistically significant descents in total proteinuria, when compared to initial levels, were observed from the beginning of the 6th month to the end of the 24th month (p
Publisher Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan
Contributor -
Date 2020-05-22
Type info:eu-repo/semantics/article
Peer-reviewed Article
Original Article
Format application/pdf
Source Medical Laboratory Technology Journal; Vol 6, No 1 (2020): June
Language eng
Relation info:eu-repo/grantAgreement/EC/FP7/000000
Rights info:eu-repo/semantics/openAccess
Copyright (c) 2020 Serhat Özçelik, Gülizar Manga Şahin

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