Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological Changes in Sublingual Glands: An Experimental Study

International Journal of Innovative Research and Reviews

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Field Value
 
Title Unrevealing of the Effect of Olfactory Bulb Lesion on Histomorphological Changes in Sublingual Glands: An Experimental Study
 
Creator Koçak, Mehmetnuri
Aydın, Mehmet Dumlu
Kaya, Zülküf
Karadeniz, Erdem
Bayramoğlu, Atıf
Ahıskalıoğlu, Ali
Aydın, Nazan
Demirci, Tuba
 
Description This study was performed to examine basic neuropathological mechanisms of undetermined effects of olfactory bulb lesion in sublingual glands. Twenty - six adult rats were randomized in three groups as control group (Group I, n=8), Sham group (Group II, n=7) and olfactory bulb lesion (OBL) group (Group III, n=11), and they all observed for the duration of eight weeks and finally euthanized. The olfactory bulbs of rat brains and sublingual glands (SLG), were extracted bilaterally. Samplings stained wit h hematoxylin/eosin and TUNEL stains to assess the stereogical olfactory bulbs volume loss degrees, and follicular volume values (FVV) of SLG per cubic centimeters. The estimated mean volumes of olfactory bulbs were as 4.87±0.33/mm3 in group I, 4.32±0.43/m m3 in group II, and 2.12±0.19/mm3 in group III (p<0.0001 and p<0.0005; in Group III vs. I, Group III vs. II, respectively). The mean volumes of FVV and degenerated neuron density of SLG were 215±56×106μm3/cm3 and 13±3/mm3 in Group I, 193 ± 44×106μm3/cm3 an d 62±11/mm3 in Group II (p<0.005), 134±27×106 μm3/cm3 and 346±83/mm3 in Group III (p<0.0001 and p<0.0005; in Group III vs. I, Group III vs. II, respectively). This study suggests that OBL may be responsible for sublingual gland degeneration, which has not been stated so far.
 
Publisher Muhammet Kaan YEŞİLYURT
 
Date 2019-12-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Text
 
Format application/pdf
 
Identifier http://www.injirr.com/article/view/40
 
Source International Journal of Innovative Research and Reviews; Vol 3 No 2 (2019): The Leonhard Euler Issue; 23-28
2636-8919
 
Language eng
 
Relation http://www.injirr.com/article/view/40/33
 
Rights Copyright (c) 2019 Mehmetnuri Koçak, Mehmet Dumlu AYDIN, Zulkuf KAYA, Erdem KARADENIZ, Atif BAYRAMOGLU, Ali AHISKALIOGLU, Nazan Aydın, Tuba Demirci
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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