Antibiotic resistance and efflux pumps

International Journal of Innovative Research and Reviews

View Publication Info
 
 
Field Value
 
Title Antibiotic resistance and efflux pumps
 
Creator Altınöz, Eda
Altuner, Ergin Murat
 
Description The main purpose of this manuscript is to review the resistance against antibiotics and efflux pumps, one of the mechanisms important in resistance against antibiotics. As a definition, the resistance against antibiotics is accepted as the capability of a microorganism to resist the activity of antimicrobials, which were successfully used to kill the microorganism once. Antibiotic resistance is characterized by several antibiotic susceptibility tests. The wide consumption of antibiotics; the over prescription of antimicrobial drugs by medical doctors; unnecessary, incorrect and inadequate self-medication by the patient and use of several antimicrobial agents either to support a healthy growth or therapeutic purposes in animals consumed as food triggered severe antibiotic resistance. Therefore, the resistance against antimicrobials became a considerable, wide-spread issue in all around the world and the studies have been initiated to overcome the resistance against antibiotics. There are several different mechanisms, which could lead bacteria to be resistant overtime. One of the mechanism of action, which leads to antibiotic resistance, is efflux pumps. Several efflux pump inhibitors were discovered until now, but since some of them are highly cytotoxic, they have very limited use. Understanding efflux pumps and discovering new inhibitors against these pumps could probably save the future of human beings.
 
Publisher Muhammet Kaan YEŞİLYURT
 
Date 2019-12-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
text
 
Format application/pdf
 
Identifier http://www.injirr.com/article/view/35
 
Source International Journal of Innovative Research and Reviews; Vol 3 No 2 (2019): The Leonhard Euler Issue; 1-9
2636-8919
 
Language eng
 
Relation http://www.injirr.com/article/view/35/31
 
Rights Copyright (c) 2019 Eda Altınöz, Ergin Murat Altuner
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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