Inflammation management in ophthalmology: new evidences for cataract surgery and beyond

AboutOpen

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Field Value
 
Title Inflammation management in ophthalmology: new evidences for cataract surgery and beyond
 
Creator Piovella, Matteo
Avitabile, Teresio
Bellucci, Roberto
Caporossi, Aldo
Marchini, Giorgio
Troiano, Pasquale
Canonico, Pier Luigi
 
Description Inflammation represents the manifestation of the host's vascular and cellular response to tissue damage, hypersensitivity of the immune system or autoimmunity. As soon as the damage is detected, the mechanisms of localization and removal of foreign substances and damaged tissues are triggered. This response is amplified by the activation of inflammatory cells and by the production of chemical mediators derived from arachidonic acid, vasoactive substances and cytokines.At the ocular level, among the different responses implemented by various inflammation mediators, the action of prostaglandins is mainly expressed in three ways: i) change of intraocular pressure; ii) induction of miosis; iii) increase of protein concentration in the aqueous humor.Ocular inflammation may continue long after the cessation of the initial cause and may also lead to serious consequences, including permanent vision reduction. For this reason, it is essential to establish a correct and effective therapeutic strategy, which allows to control inflammation, the symptoms and the clinical signs associated with it.This article therefore deals with therapeutic strategies to control inflammation, with a particular focus on the role of nonsteroidal anti-inflammatory drugs (NSAIDs) in cataract surgery.
 
Publisher Aboutscience Srl
 
Date 2019-04-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Review article
 
Format application/pdf
text/html
application/zip
 
Identifier https://journals.aboutscience.eu/index.php/aboutopen/article/view/166
10.33393/abtpn.2019.166
 
Source AboutOpen; V. 6 N. 1 (2019): January - December 2019; 5-15
AboutOpen; Vol 6 No 1 (2019): January - December 2019; 5-15
2465-2628
 
Language eng
 
Relation https://journals.aboutscience.eu/index.php/aboutopen/article/view/166/235
https://journals.aboutscience.eu/index.php/aboutopen/article/view/166/236
https://journals.aboutscience.eu/index.php/aboutopen/article/view/166/237
 
Rights Copyright (c) 2019 The authors
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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