Dabigatran in the ischemic patient undergoing atrial fibrillation ablation


View Publication Info
Field Value
Title Dabigatran in the ischemic patient undergoing atrial fibrillation ablation
Creator Spoladore, Roberto
Description Trans-catheter ablation of atrial fibrillation (AF) is a common treatment for symptomatic AF. Among the major complications of AF ablation are stroke, transient ischemic attacks and peri-procedural cardiac tamponade. Various clinical trials have shown that uninterrupted treatment with vitamin K antagonists (VKA) is associated with a lower incidence of embolic events compared to discontinuation of therapy; until recently, in the absence of equally solid evidence, this practice was not extended to the new oral anticoagulants (NOAC) not VKA due to the fear of hemorrhagic complications potentially associated with the use of an "irreversible" anticoagulant. The case of a patient suffering from numerous comorbidities is reported here. In light of the poor response to anti-arrhythmics, a TC-RF ablation was performed, with suspension of dabigatran administration only on the day of the procedure (for a total period <24 hours). Although the fear of the risk of bleeding potentially associated with the trans-catheter ablation procedure may still induce clinicians to stop anticoagulant therapy, even the decision to discontinue anticoagulant therapy with dabigatran on the day of surgery alone is challenged by recent evidence in the literature supporting the efficacy of dabigatran in reducing the incidence of hemorrhagic events during and after ablation, including the results of the RE-CIRCUIT study (Cardiology)
Publisher Aboutscience Srl
Date 2018-10-04
Type info:eu-repo/semantics/article
Case report
Format application/pdf
Identifier https://journals.aboutscience.eu/index.php/aboutopen/article/view/137
Source AboutOpen; V. 4 N. 1 (2018): January - December 2018; 154-157
AboutOpen; Vol 4 No 1 (2018): January - December 2018; 154-157
Language eng
Relation https://journals.aboutscience.eu/index.php/aboutopen/article/view/137/102
Rights Copyright (c) 2018 The authors

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us


Copyright © 2015-2018 Simon Fraser University Library