Non-traditional Route for Three Antifungal Drugs in Fungal Keratitis Treatment

Ophthalmology Research: An International Journal

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Field Value
 
Title Non-traditional Route for Three Antifungal Drugs in Fungal Keratitis Treatment
 
Creator Sedhom, Christine R
Abdel-Rahman, Mohamed S
Hussein, Mohamed S
 
Description Aims: This study aims to evaluate the efficacy of the intrastromal route of antifungal drugs in treatment of fungal keratitis.
Study Design:  Prospective non-controlled (single arm) interventional clinical study Place and Duration of Study: Ophthalmology Department, Assiut University Hospital, between March 2016 to November 2017.
Methodology: Corneal scrapings for direct smears and cultures were done for eighteen eyes of 18 consecutive patients and intrastromal injections were given according to sensitivity results.
Results: After one month of follow up of the cases in this study, 33.3% of the cases had rapid complete cure and the rest had incomplete cure with resolution of ulcer sizes by 55.34% ±6.78 after one or more intrastromal injection of antifungal drugs.
Conclusion: Intrastromal injection of antifungal drugs in treatment of fungal keratitis shows promising results in advanced cases of fungal keratitis when combined with the topical route.
 
Publisher SCIENCEDOMAIN international
 
Date 2019-06-11
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier http://journalor.com/index.php/OR/article/view/30104
10.9734/or/2019/v10i230104
 
Source Ophthalmology Research: An International Journal; 2019 - Volume 10 [Issue 2]; 1-11
2321-7227
 
Language eng
 
Relation http://journalor.com/index.php/OR/article/view/30104/56482
http://journalor.com/index.php/OR/article/view/30104/56483
 
Rights Copyright (c) 2019 © 2019 Sedhom et al.; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 

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