Comparison of Protein-C levels in diabetes melitus type 2 patients with and without ulcers at Haji Adam Malik Hospital Medan Indonesia May-July 2017

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Title Comparison of Protein-C levels in diabetes melitus type 2 patients with and without ulcers at Haji Adam Malik Hospital Medan Indonesia May-July 2017
 
Creator Zulfa, Zulfahmi; Division of Hematology and Oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Mardia, Andri I; Universitas Sumatera Utara, Medan, Indonesia
Handayani, Savita; Universitas Sumatera Utara, Medan, Indonesia
Syafril, Santi; Universitas of Sumatera Utara, Medan, Indonesia
Gatot, Dairion; Universitas Sumatera Utara, Medan, Indonesia
 
Subject
C-protein, type 2 diabetes mellitus, diabetic foot, diabetic ulcer
 
Description Introduction People with diabetes mellitus (DM) have an increased risk for thrombosis compared with non-diabetic patients. Several studies showed contradicting in data on levels of protein C in people with type 2 DM and diabetic ulcers.Methods This is a descriptive and analytical cross-sectional study on protein C concentration of patients with type 2 DM with and without foot ulcers. The control group was the type 2 DM patients without foot ulcers, whereas the case group was the type 2 DM patients with a rigid diabetic foot ulcer based on the Wagner criteria. Blood samples are then taken after 8 to 10 hours of fasting to check for protein C concentration and hemostasis examination including platelet count, prothrombin time (PT),  activated partial thromboplastin time (aPTT), thrombin time (TT), fibrinogen levels, and D-dimers.Results Of a total of 20 samples, there was no statistically significant difference in protein C levels of diabetic foot ulcers with hypercoagulation compared with no diabetic foot ulcers with hypocoagulation and no significant correlation between grade diabetic foot ulcers and protein C concentration.
 
Publisher DiscoverSys Inc.
 
Contributor
 
Date 2019-12-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://www.balimedicaljournal.org/index.php/bmj/article/view/913
10.15562/bmj.v%vi%i.913
 
Source Bali Medical Journal; Vol 8, No 3 (2019): (Available online 1 December 2019); 790-794
2302-2914
2089-1180
 
Language eng
 
Relation https://www.balimedicaljournal.org/index.php/bmj/article/view/913/pdf
 
Rights Copyright (c) 2020
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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