KARAKTERISASI NANOVESIKEL TRANSFERSOM SEBAGAI PEMBAWA “RUTIN” DALAM PENGEMBANGAN SEDIAAN TRANSDERMAL

Jurnal Ilmiah Fillia Cendekia

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Field Value
 
Title KARAKTERISASI NANOVESIKEL TRANSFERSOM SEBAGAI PEMBAWA “RUTIN” DALAM PENGEMBANGAN SEDIAAN TRANSDERMAL
 
Creator Devi Ratnasari
Effionora Anwar
 
Subject Flavonoid
Nanovesicle
Rutin
Transdermal
Transfersom
 
Description Transdermal become the alternative to deliver low solubility compound and low bioavalibility when given orally. Rutin is a flavonoid compound are found in watermelon and citrus. Rutin shows a low absorption when administered orally so the alternative is given in the transdermal route. A variety of approaches taken to increase the penetration of transdermal, one with nanovesikel carrier system. Transfersome is nanovesicle 200-300 nm sized composed of phospholipids, surfactants and water to increase penetration in trasndermal route. This study was to characterization transfersome containing rutin. The result show the size of transfersome < 150 nm, polydispersity index about 0.1 to 0.3, zeta potential less than -30 mV and entrapment efficiency > 80%.
 
Publisher Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
 
Date 2016-06-13
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://ejournal.sttif.ac.id/index.php/farmamedika/article/view/40
10.47219/ath.v1i1.40
 
Source Jurnal Farmamedika (Pharmamedika Journal); Vol 1 No 1 (2016): Jurnal Farmamedika (Pharmamedica Journal); 12-18
2686-4487
2502-6011
10.47219/ath.v1i1
 
Language eng
 
Relation https://ejournal.sttif.ac.id/index.php/farmamedika/article/view/40/36
 
Rights Copyright (c) 2016 Farmamedika (Pharmamedika Journal)
https://creativecommons.org/licenses/by/4.0
 

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