Antioxidant and Anti-aging activity of Moringa Leaves Extract Body Butter

Jurnal Ilmu Kefarmasian Indonesia

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Title Antioxidant and Anti-aging activity of Moringa Leaves Extract Body Butter
Uji Aktivitas Antioksidan dan Anti Aging Body Butter dengan Bahan Aktif Ekstrak Daun Kelor
 
Creator Nurulita, Nunuk Aries
Sundhani, Elza
Amalia, Irma
Rahmawati, Fifi
Dian Utami, Nina Nurhayati
 
Description Moringa leaf (Moringa oleifera) was one of plants that containt phenol compounds such as alkaloid, tannin, saponin and flavonoid that were useful as a antioxidant and anti aging. The aim of this research was to prove antioxidant and anti aging’s activity of Moringa leaf. The extraction process of Moringa leaf using Maseration method with ethanol solvent 70 % ratio 1:10, then the antioxidant properties determinate using beta carotene bleaching (BCB) and anti aging’s activity test was done, after that formulated the body butter with activeingredient of Moringa leaf extract 0,5 %. Moringa extract contains total phenolic 10,45 mg GAE/g extract and 5,53 % of total flavonoid. The result showed that Moringa leaf extract had inhibition of beta carotene bleaching properties as shown by BCB results. Moringa leaf extract inhibit the collagenase activity until 47,25 % at concentration of 1600 ppm. Moringa leaf extract body butter has high potency of antiaging through antioxidant and collagenase inhibitor mechanism. Moringa body butter had good organoleptic properties. However the physical properties of moringa body butter should be optimozed its composition to get the better one.
Daun Kelor  (Moringa oleifera) merupakan salah satu tanaman yang mengandung senyawa fenol seperti alkaloid tannin saponin dan flavonoid yang berkhasiat sebagai antioksidan dan anti  aging. Penelitian ini bertujuan untuk membuktikan aktivitas antioksidan dan anti aging daun kelor serta membuat Formulasi Body Butter dari ekstrak daun kelor. Proses ekstraksi daun kelor metode Maserasi dengan pelarut etanol 70 % perbandingan 1:10 kemudian dilakukan uji aktivitas antioksidan dengan metode beta caroten bleaching (BCB) dan anti aging selanjutnya dilakukan formulasi body butter dengan bahan aktif ekstrak daun kelor 0,5 %. Hasil penetapan kadar Fenolik total dan Flavonoid total ekstrak daun kelor menunjukkan kadar yang dihasilkan yaitu sebesar 10,45 mgGAE/g ekstrak untuk fenolik total dan 5,53 % untuk Flavonoid Total. Hasil penelitian menunjukkan bahwa ekstrak daun kelor memiliki aktivitas penghambatan proses pemucatan beta karoten (inhibitor BCB) dan inhibitor enzim kolagenase dengan persentase penghambatan sebesar 47 %. Body Butter ekstrak daun kelor mempunyai potensi sebagai antiaging melalui mekanisme anti oksidan dan inhibitor kolagenase. Body butter ekstrak daun kelor mempunyai penampakan organoleptis yang sudah baik dan menarik. Namun sifat fisik dari moringa body butter masih memerlukan optimasi agar lebih baik dan memenuhi standar yang telah ditetapkan.
 
Publisher Fakultas Farmasi Universitas Indonesia
 
Date 2019-04-22
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/543
10.35814/jifi.v17i1.543
 
Source JURNAL ILMU KEFARMASIAN INDONESIA; Vol 17 No 1 (2019): JIFI; 1-8
2614-6495
1693-1831
 
Language eng
 
Relation http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/543/472
 
Rights Copyright (c) 2019 JURNAL ILMU KEFARMASIAN INDONESIA
 

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