Evaluation of Drug Side Effects Chemotherapy on Quality of Life (QOL) Breast Cancer Patients at Hospital X in Jakarta

Jurnal Ilmu Kefarmasian Indonesia

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Title Evaluation of Drug Side Effects Chemotherapy on Quality of Life (QOL) Breast Cancer Patients at Hospital X in Jakarta
Evaluasi Efek Samping OBat Kemoterapi terhadap Quality of Life (QOL) Pasien Kanker Payudara di Rumah Sakit X Jakarta
 
Creator Khairani, Sondang
Keban, Sesilia A
Afrianty, Meyke
 
Description Breast cancer is the number one cancer type discovered at women in the world. Most causes are genetic factors and hormonal factors. One cancer treatments with chemotherapy. Chemotherapy drugs active in cells dividing and reproducing, but cells normally to be affected by chemotherapy and side effects from chemotherapy drugs affect quality of life. The aim of the study to evaluate side effects of chemotherapy drugs on the quality of life of breast cancer patients. Sampling technique observational prospective breast cancer patients with completed the chemotherapy cycle from September 2017 to April 2018 with descriptive analysis and statistics by looking correlation between drug side effects and Quality of Life (QoL). Results of the study were side effects of fatigue 100%, nausea 67,5%, vomiting 60%, no appetite 63,75%, fever 42,5%, joint pain 43,75%, diarrhea 16,25%, difficulty swallowing 16,25%, allergies 5%, itching 1,25%, mouth sores 3,75%, swollen right hand 1,25%, constipation 3,75%. QoL results are physical 6,2%; psychology 5,3%; social 4,9%; spiritual 6,8%. Results of Sperman test showed no correlation between the side effects of chemotherapy and QoL P> 0,05. This study shows that there is no relationship between the side effects drug chemotherapy and QoL in breast cancer patients.
Kanker payudara merupakan jenis kanker nomor satu ditemui pada wanita di dunia. Penyebab terbanyak disebabkan oleh faktor genetik dan faktor hormonal. Salah satu pengobatan kanker dengan  kemoterapi. Obat kemoterapi aktif pada sel yang sedang membelah dan bereproduksi, namun sel yang normal tidak tertutup kemungkinan akan terpengaruh kemoterapi dan muncul efek samping dari obat kemoterapi yang mempengaruhi kualitas hidup. Tujuan penelitian yaitu mengevaluasi efek samping obat kemoterapi terhadap kualitas hidup pasien kanker payudara. Teknik sampling prospektif observasional terhadap pasien kanker payudara yang sudah menyelesaikan siklus kemoterapi periode September 2017 sampai April 2018 dengan analisis deskriptif dan statistik dengan melihat korelasi antara efek samping obat dan Quality of Life (QoL). Hasil penelitian yaitu terdapat efek samping kelelahan (100%), mual (67,5%), muntah (60%), tidak ada nafsu makan (63,75%), demam (42,5%), sakit pada persendian (43,75%), diare (16,25%), sulit menelan (16,25%), alergi (5 %), gatal (1,25%), ada luka dimulut (3,75%), bengkak tangan kanan (1,25%), sembelit (3,75%). Hasil QoL yaitu domain fisik 6,2%; psikologi 5,3%; sosial 4,9%; spiritual 6,8%. Hasil uji sperman menunjukan tidak ada korelasi antara efek samping kemoterapi dan QoL P>0.05. Penelitian ini menunjukkan bahwa tidak ada hubungan antara efek samping obat kemoterapi dan QoL pada pasien kanker payudara.
 
Publisher Fakultas Farmasi Universitas Indonesia
 
Date 2019-04-24
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/705
10.35814/jifi.v17i1.705
 
Source JURNAL ILMU KEFARMASIAN INDONESIA; Vol 17 No 1 (2019): JIFI; 9-13
2614-6495
1693-1831
 
Language eng
 
Relation http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/705/476
 
Rights Copyright (c) 2019 JURNAL ILMU KEFARMASIAN INDONESIA
 

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