Neonatal Growth, Neurotrophine, Zinc, and Ferritin Concentration in Normal and Iron Deficience Pregnancy: An Observational Analitic Study

Journal of Business & Economics Research (JBER)

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Title Neonatal Growth, Neurotrophine, Zinc, and Ferritin Concentration in Normal and Iron Deficience Pregnancy: An Observational Analitic Study
 
Creator Yusrawati, Yusrawati
Defrin, Defrin
Karmia, Hudila Rifa
 
Subject Normal and Iron Deficience Pregnancy
Neonatal Growth
Neurotrophine
Zinc
Ferritin
 
Description BACKGROUND: Anemia in pregnancy was one of the national problems. Insufficient iron deposits before pregnancy and inadequate iron intake during pregnancy could lead to iron deficiency anaemia in pregnancy, followed by iron deficiency in neonates.
AIM: This study aimed to assess the molecular relationship of maternal iron deficiency with the function of the neonatal central nervous system to know the cognitive aspects of learning ability of children.
METHODS: This study was an observational analytic study with cross-sectional design underwent in RSUP Dr M. Djamil Padang, RSI Ibnu Sina Padang, and RSU BMC Padang. The sample size was 80 pregnant women at term. After a maternal and neonatal physical examination, maternal and umbilical blood samples were obtained to assess maternal ferritin levels and neonates ferritin, neurotrophin and zinc levels using the Enzyme-Linked Immunosorbent Assay (ELISA). Data were analysed using the IBM SPSS Statistics for Windows. The independent sample t-test was performed to assess the relationship for normally distributed data and Mann-Whitney test for abnormal data distribution with significance level p < 0.05.
RESULTS: There were differences in mean neonatal ferritin (p < 0.001), neonatal neurotrophin (p < 0.001), and neonatal zinc (p < 0.001) to normal maternal ferritin levels (≥ 15 μg/ml) and low maternal ferritin levels (< 15 μg/ml). The difference in mean neonatal head circumference (0.92; CI95% -0.79-0.98) was associated with neonatal ferritin levels.
CONCLUSIONS: The mean neonatal ferritin, neurotrophin, and zinc levels were found lower in iron deficiency maternal. Maternal iron deficiency correlates with neonate growth, iron deficiency, and neurotrophin expression that affected neonate cognition.
 
Publisher Scientific Foundation SPIROSKI, Skopje, Republic of Macedonia; ID Design 2012/DOOEL Skopje, Republic of Macedonia
 
Date 2019-04-14
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
application/pdf
 
Identifier https://www.id-press.eu/mjms/article/view/oamjms.2019.202
10.3889/oamjms.2019.202
 
Source Open Access Macedonian Journal of Medical Sciences; Vol 7 No 7 (2019): Apr 15 (OAMJMS); 1114-1118
1857-9655
 
Language eng
 
Relation https://www.id-press.eu/mjms/article/view/oamjms.2019.202/3210
https://www.id-press.eu/mjms/article/view/oamjms.2019.202/3184
 
Rights Copyright (c) 2019 Yusrawati Yusrawati, Defrin Defrin, Hudila Rifa Karmia
https://creativecommons.org/licenses/by-nc/4.0
 

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