PSEUDOCHOLINESTERASE AS A PREDICTOR MARKER IN HYPOTHYROID PATIENTS

International Journal of Clinical and Biomedical Research

View Publication Info
 
 
Field Value
 
Title PSEUDOCHOLINESTERASE AS A PREDICTOR MARKER IN HYPOTHYROID PATIENTS
 
Creator GG, Kaushik
Reena, Soni
 
Description Introduction: Hypothyroidism is due to decreased circulating levels of Thyroid hormones and is caused by inadequate functioning of thyroid gland. Pseudocholinesterase (PCHE) is a nonspecific cholinesterase enzyme that hydrolyses choline based esters in plasma. The purpose of this study was to evaluate the serum level of PCHE in hypothyroid patients. Methodology: The present study was conducted on 100 newly diagnosed hypothyroid patients attending the Medical OPD. The results of patients were compared with 100 healthy controls of either sex of similar age group. Anthropometric measurements, T3, T4, TSH, PCHE & Cholesterol estimations were performed. Results: The mean serum PCHE (decrease) level was observed statistically highly significant (p<0.001) in hypothyroid patients as compared with healthy control subjects.  A highly significant positive correlation between PCHE with T3 & T4 (p< 0.001) in hypothyroid cases. Conclusion: Serum Pseudocholinesterase may be helpful as biomarker in screening test  for hypothyroidism along with thyroid stimulating hormone.
 
Publisher Sumathi Publications
 
Contributor
 
Date 2018-07-31
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://sumathipublications.com/index.php/ijcbr/article/view/221
10.31878/ijcbr.2018.43.06
 
Source International Journal of Clinical and Biomedical Research; Volume 4, Issue 3; July 2018; 27-29
2395-0471
2521-0394
 
Language eng
 
Relation http://sumathipublications.com/index.php/ijcbr/article/view/221/254
 
Rights Copyright (c) 2018 Kaushik GG, Soni Reena
https://creativecommons.org/licenses/by-nc-sa/4.0
 

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