AN EVALUATION OF FIXED DOSE COMBINATIONS (FDCs) USED FOR TREATMENT DIABETES IN INDIAN MARKET

International Journal of Current Research in Physiology and Pharmacology (IJCRPP)

View Publication Info
 
 
Field Value
 
Title AN EVALUATION OF FIXED DOSE COMBINATIONS (FDCs) USED FOR TREATMENT DIABETES IN INDIAN MARKET
 
Creator Kamni, Supreet
Naikwadi, Akram A
Khot, Anant
 
Description Objective: - To analyse the rationality of various FDCs used in the treatment Diabetes Mellitus and to find out the irrational FDCs existing in Indian market. Material and Methods: - Study Design: Analytical study. Data on FDC’s available in the Indian market was collected from Current Index of Medical Specialities (CIMS) and Monthly Index of Medical Specialities (MIMS) and their rationality was analysed using a pretested tool based on FDCs listed in WHO essential list of medicines and National List of Essential Medicines (NLEM), others based on their pharmacodynamic activity, Pharmacokinetic parameters and significant drug interactions occurring due to API (Active pharmaceutical ingredients) contained within the product Result: A total of 18 combinations were analysed, among those 11 combinations were irrational. Conclusion: Predominantly irrational FDCs are being circulated in the Indian market hence through analyses by prescribers is needed before prescribing to patients in order to avoid ADR. This calls for a close scrutiny of marketed FDCs and educating prescribers to use them with great care and caution also indicates a serious review of regulatory framework for drug manufacturing and marketing.KEYWORDS: Fixed Dose Combinations, antidiabetics, irrational.
 
Publisher Sumathi Publications
 
Contributor
 
Date 2018-10-29
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://www.sumathipublications.com/index.php/ijcrpp/article/view/231
10.31878/ijcrpp.2018.21.2
 
Source International Journal of Current Research in Physiology and Pharmacology (IJCRPP); Vol 2, No 1 (2018); 6-9
2523-6709
2523-6695
 
Language eng
 
Relation http://www.sumathipublications.com/index.php/ijcrpp/article/view/231/268
 
Rights Copyright (c) 2018 Supreet Kamni, Akram A Naikwadi, Anant Khot
https://creativecommons.org/licenses/by-nc-sa/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library