THE EFFECT OF MANGROVE (Rhizophora apiculata) BARK EXTRACT ETHANOL ON HISTOPATHOLOGY PANCREAS OF MALE WHITE RATS SPRAGUE DAWLEY STRAIN EXPOSED TO CIGARETTE SMOKE

Acta Biochimica Indonesiana

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Title THE EFFECT OF MANGROVE (Rhizophora apiculata) BARK EXTRACT ETHANOL ON HISTOPATHOLOGY PANCREAS OF MALE WHITE RATS SPRAGUE DAWLEY STRAIN EXPOSED TO CIGARETTE SMOKE
 
Creator Mustofa, Syazili
Bahagia, W
Kurniawaty, Evi
Audah, Kholis A
 
Description Background: Cigarette smoke is free radical that causing some pathological conditions such as inflammation, proteolysis, and oxidative stress. In previous studies, mangrove (Rhizophora apiculata) bark extract showed the potential effect as an antioxidant. Mangrove and mangrove associates are abundant plants that grow throughout Indonesian shorelines that have high pharmaceutical and food values.Objective: The purpose of this study is to explore the potential of Rhizophora apiculata bark extract in protecting pancreas of male white rat (Rattus novergicus) Sprague Dawley strain exposed to cigarette smoke.Methods: This research was an experimental study using a posttest-only control group design. Mangrove bark was extracted by using the maceration method. Cigarette smoke exposure was performed using an electric cigarette. Liver inflammation is assessed histopathologically.Results: Significant results (p <0.05) were found between the control and cigarette groups as well as the cigarette and bark extract + control groups. The results were not significant (p> 0.05) between the control and the bark extract + cigarette.Conclusion : The administration of mangrove bark extract has a potential to protect the damage of pancreatic male white rats (Rattus norvegicus) Sprague Dawley strains exposed to cigarette smoke
 
Publisher PP PBBMI
 
Contributor
 
Date 2018-10-09
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://pbbmi.org/jurnal/index.php/ActaBioIna/article/view/2
10.32889/actabioina.v1i1.2
 
Source Acta Biochimica Indonesiana; Vol 1, No 1 (2018): ACTA BIOCHIMICA INDONESIANA; 7-13
2654-3222
2654-6108
 
Language eng
 
Relation https://pbbmi.org/jurnal/index.php/ActaBioIna/article/view/2/4
 
Rights Copyright (c) 2018 Acta Biochimica Indonesiana
 

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