Comparison Between The Efficacy of Fentanyl Continuous Infusion and Intratechal Morphine for Pain After Cesarean Section

Sains Medika

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Title Comparison Between The Efficacy of Fentanyl Continuous Infusion and Intratechal Morphine for Pain After Cesarean Section
 
Creator Putro, Prabowo Wicaksono Yuwono
Nasihun, Taufiqurrachman
 
Subject Pain; cpain, caesarean section, intrathecal morphine, fentanyl continuous infusion, disposable elastomeric pump, NRS, OOAPS, cortisolaesarean section; intrathecal morphine, fentanyl continuous infusion, disposable elastomeric pump; NRS; OOAPS; cortisol.
 
Description Background: Intrathecal morphine has been shown to be effective for pain after cesarean section with possible side effect including delayed respiratorydepression, nausea vomiting and pruritus. Fentanyl continuous infusion fixed base infusion rate with disposable elastomeric pump is an alternative tointrathecal morphine but has not been been widely studied.  Objective: to compare the effectiveness between fentanyl continuous infusion fixed base infusion rate using disposable elastomeric pump and intrathecal morphine. Methods: in a Randomized Controlled Trial (RCT), 56 patients meeting the inclusion criteria were divided into two groups: Morphine group (n=28):spinal anesthesia 10 mg Bupivacaine Heavy 0.5% + 100 mcg morphine; Fentanyl group (n=28): spinal anesthesia 10 mg Bupivacaine Heavy 0.5% +fentanyl continuous infusion 0.5 mcg/kg BW/hour using disposable elastomeric pump after delivery. Data analysis: Mann-Whitney test at the level ofsignificance p<0.05. Results: Analgesic effect of Fentanyl group was as effective as that of Morphine group. NRS score difference was significant only in measurement taken 6hours after surgery (p=0.034). Mean NRS score for Morphine and Fentanyl were 68±1.02 and 1.11±0.832, respectively. Both group were effective in preventing increased cortisol level measured 6 hours after surgery, mean value group Morphine and Fentanyl were 15.053±8.664 and12.162±8.623,respectively.There were no statistical significant difference between groups (p=0.114). No significant difference in side effect between the groups was found. Conclusion:Fentanyl continuous infusion 0.5 mcg/kg BW/hour using disposable elastomeric pump is as effective as intrathecal morphine 100 mcg/kg BW/hour
 
Publisher Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)
 
Contributor
 
Date 2018-04-06
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1842
10.26532/sainsmed.v8i2.1842
 
Source Sains Medika: Jurnal Kedokteran dan Kesehatan; Vol 8, No 2 (2017): July-Desember 2017
2339-093X
2085-1545
10.26532/sainsmed.v8i2
 
Language eng
 
Relation http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1842/pdf
 
Rights Copyright (c) 2018 Sains Medika
http://creativecommons.org/licenses/by/4.0
 

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