DETECTION OF HUMAN HERPESVIRUS-8 ANTIGEN IN HIV-INFECTED PATIENTS IN EAST JAVA, INDONESIA

African Journal of Infectious Diseases (AJID)

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Title DETECTION OF HUMAN HERPESVIRUS-8 ANTIGEN IN HIV-INFECTED PATIENTS IN EAST JAVA, INDONESIA
 
Creator Oktafiani, Devi
Megasari, Ni Luh Ayu
Fitriana, Elsa
Nasronudin, Nasronudin
Lusida, Maria Inge
Soetjipto, Soetjipto
 
Subject Traditional Medicine, Medicinal Plants
HHV-8 antigen, HIV-positive, East Java, Indonesia.
 
Description Background: Co-infection of human herpesvirus-8 (HHV-8) in HIV-positive people might cause Kaposi's sarcoma. Early
detection of HHV-8 may prevent the onset of clinical manifestations. In Indonesia, detection of HHV-8 antigen in HIVpositive
patients has yet to be reported. The intention of this research was to examine the presence of HHV-8 antigen in
HIV-positive patients in East Java, Indonesia.
Material and Methods: 103 serum samples were collected from HIV-positive patients in Surabaya and Tulungagung, East
Java, Indonesia. Serums were then tested for the presence of HHV-8 antigen by using sandwich ELISA.
Results: Human Herpesvirus-8 antigen was detected in 15 samples (14.5%). The presence of HHV-8 infection in HIVpositive
patients did not present differently in males and females and among different age groups. Human
immunodeficiency virus-positive serum samples were collected from 23 homosexual men, 25 intravenous drug users
(IVDUs) and 52 heterosexuals. In the male homosexual group, HHV-8 antigen was detected in 21.7% (5/23) of the
samples, while in the intravenous drug user group (IVDUs), 16% (4/25) of the samples were found to have HHV-8 antigen.
Conclusion: This research found the presence of HHV-8 antigen in 14.5% of patients in East Java, Indonesia. It is
recommended that patients with a positive result should receive further examination to detect any clinical manifestations
related to HHV-8 infection, especially in the form of Kaposi’s sarcoma lesions, so that the illness can be appropriately
managed.
 
Publisher African Traditional Medicine Supporters Initiative (ATHMSI), 7, Road 1, Otunmaiye Square
 
Contributor LSM Mahameru, KDS Couple Community, and all the colleagues who have helped in this study.
 
Date 2018-06-18
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://journals.sfu.ca/africanem/index.php/AJID/article/view/5112
10.21010/Ajid.v12i2.7
 
Source African Journal of Infectious Diseases (AJID); Vol 12, No 2 (2018); 43-46
2505-0419
2006-0165
 
Language eng
 
Relation http://journals.sfu.ca/africanem/index.php/AJID/article/view/5112/3144
 
Coverage Africa


 
Rights Copyright (c) 2018 African Journal of Infectious Diseases (AJID)
http://creativecommons.org/licenses/by/4.0
 

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