SYNTHESIS AND BIOLOGICAL ACTIVITY EVALUATION OF SOME DERIVATIVES SYNTHESIZED FROM CURCUMIN AND CURCUMIN ANALOG

Hue University Journal of Science: Natural Science

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Field Value
 
Title SYNTHESIS AND BIOLOGICAL ACTIVITY EVALUATION OF SOME DERIVATIVES SYNTHESIZED FROM CURCUMIN AND CURCUMIN ANALOG
 
Creator Hoàn, Dương Quốc
 
Description The acetohydrazides A5 containing an isoxazole ring and B5 containing an indazole ring were synthesized from the corresponding acetohydrazide derivatives with acetic anhydride in about 80% high yield. Also, two acetohydrazones B6 and B7 were driven from acetohydrazide B4 by condensation reaction. Bioactivity testes showed that none of them were active against on bacteria except acetohydrazones  B7 showing moderate reactivity against KB cancer cell line at IC50 = 57 mg/L.
 
Publisher Hue University
 
Contributor
 
Date 2017-07-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion


 
Identifier http://joshueuni.edu.vn/index.php/HUJOS-NS/article/view/4139
10.26459/jns.v126i1B.4139
 
Source Khoa học Tự Nhiên; Vol 126, No 1B (2017): Hue University Journal of Science: Natural Science
Hue University Journal of Science: Natural Science; Vol 126, No 1B (2017): Hue University Journal of Science: Natural Science
1859-1388
1859-1388
10.26459/jns.v126i1B
 
Language en
 
Rights Copyright (c) 2017 Journal of Natural Science
 

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