Antibiotic Sensitivity Pattern in Neonatal Septicemia at Tertiary Care Hospital

Asian Pacific Journal of Health Sciences

View Publication Info
 
 
Field Value
 
Title Antibiotic Sensitivity Pattern in Neonatal Septicemia at Tertiary Care Hospital
 
Creator J. Ghedia Bindiya
Manish R. Shah
 
Subject Antibiotic sensitivity pattern, Disc diffusion method, Gram-negative bacteria, Gram-positive bacteria, Neonatal septicemia
 
Description Background: There is real shortage of national data on antimicrobial resistance rates in Indian neonates. A descriptive review was conducted to determine the patterns of antimicrobial resistance in isolates of blood stream infection among neonates in Jamnagar, Gujarat, India. Materials and Methods: The study was carried out in a tertiary care hospital from a period of March 1, 2014, to August 31, 2015. This is a non-randomized, prospective study in which 109 cases of suspected neonatal septicemia on the basis of antenatal high-risk factors and signs and symptoms of sepsis during this period were studied. Results: A total number of 109 neonates with clinically suspected neonatal septicemia were studied. Sixty-nine (63.3%) cases out of them were blood culture positive. Out of 69 positive cases, in one sample, two organisms were isolated. Hence, the total number of organisms was 70. Out of these 70 organisms, 44 were Gram-positive cocci, 23 were Gram-negative bacilli, and three were Candida spp. Gram-positive cocci were more sensitive to linezolid, vancomycin, and clindamycin whereas Gram-negative bacilli were more sensitive to ampicillin, ofloxacin, and amikacin. Antimicrobial sensitivity of fungal isolates was not done as the antifungal discs were not available. Conclusion: The Gram-positive organisms are the frequent cause of neonatal septicemia so when neonatal septicemia is suspected, drugs of choice for Gram-positive organisms are linezolid, vancomycin, and clindamycin and for Gram-negative organism drugs of choice are ampicillin, ofloxacin, and amikacin.
 
Publisher IJPMR Publishing Press
 
Date 2022-01-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://www.apjhs.com/index.php/apjhs/article/view/1932
 
Source Asian Pacific Journal of Health Sciences; Vol. 9 No. 1 (2022): Vol 9 | Issue 1 | January - March 2022; 70-74
2349-0659
2350-0964
 
Language eng
 
Relation https://www.apjhs.com/index.php/apjhs/article/view/1932/1278
 
Rights Copyright (c) 2022 J. Ghedia Bindiya, Manish R. Shah
https://creativecommons.org/licenses/by/4.0
 

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